null

SMILES On1c(=O)[nH]c2cc(sc2c1=O)-c1ccccc1

InChI Key InChIKey=AUGRTFPCHUPOTH-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50157834   

TargetFlap endonuclease 1(Homo sapiens (Human))
Athersys, Inc.

Curated by ChEMBL
LigandPNGBDBM50157834(3-Hydroxy-6-phenyl-1H-thieno[3,2-d]pyrimidine-2,4-...)copy SMILEScopy InChI
Affinity DataIC50: 0.146nMAssay Description:Inhibitory concentration against the Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7V46PubMed
TargetDNA excision repair protein ERCC-5(Homo sapiens (Human))
Athersys, Inc.

Curated by ChEMBL
LigandPNGBDBM50157834(3-Hydroxy-6-phenyl-1H-thieno[3,2-d]pyrimidine-2,4-...)copy SMILEScopy InChI
Affinity DataIC50: 0.202nMAssay Description:Inhibitory concentration against the xeroderma pigmentosum GMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7V46PubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50157834(3-Hydroxy-6-phenyl-1H-thieno[3,2-d]pyrimidine-2,4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of polymerase activity of recombinant HIV1 reverse polymerase assessed as reduction in extension of an 18 nucleotide DNA primer using temp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58PW6PubMed
TargetIntegrase(Human immunodeficiency virus 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50157834(3-Hydroxy-6-phenyl-1H-thieno[3,2-d]pyrimidine-2,4-...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of HIV1 integrase pre-incubated for 10 mins before DNA substrate addition and measured after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58PW6PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50157834(3-Hydroxy-6-phenyl-1H-thieno[3,2-d]pyrimidine-2,4-...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of RNH activity of recombinant HIV1 reverse transcriptase RNase H assessed as reduction in internal cleavage of RNA strand using RNA/DNA d...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58PW6PubMed