null

SMILES CC(C)ON(CC(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=PHGLPDURIUEELR-UHFFFAOYSA-N

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 38 hits for monomerid = 50161331   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8DXNPubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))TBA
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 200nMMore data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8DXNPubMed
TargetCollagenase 3(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8DXNPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8DXNPubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))TBA
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human recombinant MMP14More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8DXNPubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human recombinant MMP14 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))TBA
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of MMP9 by fluorometric assayMore data for this Ligand-Target Pair
TargetMatrilysin(Homo sapiens (Human))
University of Athens

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4WM2PubMed
TargetStromelysin-1(Homo sapiens (Human))
University of Athens

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4WM2PubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4WM2PubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4WM2PubMed
TargetStromelysin-1(Homo sapiens (Human))
University of Athens

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8DXNPubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8DXNPubMed
TargetCollagenase 3(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of MMP13-mediated collagen degradation by SDS-PAGEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8DXNPubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Inhibition of human recombinant MMP16More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8DXNPubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8DXNPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of MMP1-mediated collagen degradation by SDS-PAGEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8DXNPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of MMP1 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of MMP2 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of human recombinant ADAM17 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HK0PubMed
TargetStromelysin-1(Homo sapiens (Human))
University of Athens

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of human matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34Z6TPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of human matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34Z6TPubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human matrix metalloprotease-14More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34Z6TPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34Z6TPubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))TBA
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human matrix metalloprotease-14More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34Z6TPubMed
TargetMatrilysin(Homo sapiens (Human))
University of Athens

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human matrix metalloprotease-7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34Z6TPubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))TBA
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of MMP9 (unknown origin)More data for this Ligand-Target Pair
TargetStromelysin-1(Homo sapiens (Human))
University of Athens

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of MMP3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC91CRPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC91CRPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 12nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB281XPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB281XPubMed
TargetStromelysin-1(Homo sapiens (Human))
University of Athens

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB281XPubMed
TargetMatrilysin(Homo sapiens (Human))
University of Athens

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB281XPubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))TBA
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of MMP13-mediated collagen degradation by SDS-PAGEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8DXNPubMed