null

SMILES CC(C)c1cc(Oc2c(Br)cc3[nH]c(cc3c2Br)C(O)=O)ccc1O

InChI Key InChIKey=PKPVFOLUOGCXPY-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50178974   

TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

Curated by ChEMBL
LigandPNGBDBM50178974(4,6-dibromo-5-(4-hydroxy-3-isopropylphenoxy)-1H-in...)copy SMILEScopy InChI
Affinity DataIC50: 0.280nMAssay Description:Inhibition of human TRbeta1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72H1WPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

Curated by ChEMBL
LigandPNGBDBM50178974(4,6-dibromo-5-(4-hydroxy-3-isopropylphenoxy)-1H-in...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human TRalpha1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72H1WPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

Curated by ChEMBL
LigandPNGBDBM50178974(4,6-dibromo-5-(4-hydroxy-3-isopropylphenoxy)-1H-in...)copy SMILEScopy InChI
Affinity DataIC50: 2.51nMAssay Description:Inhibition of thyroid hormone receptor alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37XJQPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

Curated by ChEMBL
LigandPNGBDBM50178974(4,6-dibromo-5-(4-hydroxy-3-isopropylphenoxy)-1H-in...)copy SMILEScopy InChI
Affinity DataEC50:  10nMAssay Description:Efficacy against TRAF-alpha-1 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72H1WPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

Curated by ChEMBL
LigandPNGBDBM50178974(4,6-dibromo-5-(4-hydroxy-3-isopropylphenoxy)-1H-in...)copy SMILEScopy InChI
Affinity DataIC50: 0.282nMAssay Description:Inhibition of thyroid hormone receptor betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37XJQPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

Curated by ChEMBL
LigandPNGBDBM50178974(4,6-dibromo-5-(4-hydroxy-3-isopropylphenoxy)-1H-in...)copy SMILEScopy InChI
Affinity DataEC50:  4.20nMAssay Description:Efficacy against TRAF-beta-1 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72H1WPubMed