null
SMILES Cc1cc(COc2ccc(cc2)C(=O)NC2(CC(=O)NO)CCOCC2)c2ccccc2n1
InChI Key InChIKey=NUVSGXIVCJBRBF-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 29 hits for monomerid = 50183715
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
University of Athens
Curated by ChEMBL
University of Athens
Curated by ChEMBL
Affinity DataKi: 0.350nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
University of Athens
Curated by ChEMBL
University of Athens
Curated by ChEMBL
Affinity DataKi: 0.350nMAssay Description:Inhibition of porcine TACEMore data for this Ligand-Target Pair
TargetMatrilysin(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 25nMAssay Description:Binding affinity to MMP7More data for this Ligand-Target Pair
TargetMatrilysin(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
TargetStromelysin-1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 82nMAssay Description:Binding affinity to MMP3More data for this Ligand-Target Pair
TargetStromelysin-1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 1.90E+3nMAssay Description:Binding affinity to ADAMTS5More data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 1.90E+3nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: >2.13E+3nMAssay Description:Binding affinity to MMP9More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: >2.13E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
Affinity DataKi: >3.10E+3nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
Affinity DataKi: >3.10E+3nMAssay Description:Binding affinity to MMP8More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: >3.33E+3nMAssay Description:Binding affinity to MMP2More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: >3.33E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 4.60E+3nMAssay Description:Binding affinity to ADAMTS4More data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 4.60E+3nMAssay Description:Inhibition of ADAMTS4More data for this Ligand-Target Pair
Affinity DataKi: >4.95E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
Affinity DataKi: >4.95E+3nMAssay Description:Binding affinity to MMP1More data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: >5.03E+3nMAssay Description:Binding affinity to MMP13More data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: >5.03E+3nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: >5.29E+3nMAssay Description:Binding affinity to MMP14More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: >5.29E+3nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
Affinity DataKi: >5.55E+3nMAssay Description:Inhibition of MMP16More data for this Ligand-Target Pair
Affinity DataKi: >5.55E+3nMAssay Description:Binding affinity to MMP16More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: >7.09E+3nMAssay Description:Binding affinity to MMP15More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: >7.09E+3nMAssay Description:Inhibition of MMP15More data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 1(Homo sapiens (Human))
University of Athens
Curated by ChEMBL
University of Athens
Curated by ChEMBL
Affinity DataKi: 7.80E+3nMAssay Description:Inhibition of ADAMTS1More data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 1(Homo sapiens (Human))
University of Athens
Curated by ChEMBL
University of Athens
Curated by ChEMBL
Affinity DataKi: 7.80E+3nMAssay Description:Binding affinity to ADAMTS1More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of LPS-stimulated TNFalpha production in human whole bloodMore data for this Ligand-Target Pair