null

SMILES NC(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccc2OCCOc2c1)-c1ccccn1

InChI Key InChIKey=DPDZHVCKYBCJHW-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50229971   

TargetCasein kinase I isoform delta(Rattus norvegicus (rat))
Eberhard-Karls-University

Curated by ChEMBL
LigandPNGBDBM50229971(4-(4-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-5-pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of GST-fused rat CK1delta expressed in Escherichia coli using phosphorylated peptide TFRPRTSpSNASTIS as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7961PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University

Curated by ChEMBL
LigandPNGBDBM50229971(4-(4-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-5-pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of GST-fused human p38alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7961PubMed
TargetCasein kinase I isoform delta(Rattus norvegicus (rat))
Eberhard-Karls-University

Curated by ChEMBL
LigandPNGBDBM50229971(4-(4-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-5-pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 353nMAssay Description:Inhibition of rat CK1delta in presence of 20 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52R2MPubMed
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50229971(4-(4-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-5-pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of CK1 using KRRRALS(p)VASLPGL as substrate after 40 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2J2FPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University

Curated by ChEMBL
LigandPNGBDBM50229971(4-(4-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-5-pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of p38-alpha MAPK in the presence of 50uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27082B4PubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50229971(4-(4-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-5-pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of CK1delta in the presence of 100uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27082B4PubMed
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM50229971(4-(4-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-5-pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 338nMAssay Description:Inhibition of human CK1E using KRRRAL[pS]VASLPGL as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W380MTPubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50229971(4-(4-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-5-pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of CK1deltaChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB82RHPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University

Curated by ChEMBL
LigandPNGBDBM50229971(4-(4-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-5-pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of ALK5Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB82RHPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University

Curated by ChEMBL
LigandPNGBDBM50229971(4-(4-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-5-pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of p38alphaChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB82RHPubMed
TargetCasein kinase II subunit alpha(Schizosaccharomyces pombe 972h-)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50229971(4-(4-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-5-pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of Schizosaccharomyces pombe CK1Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB82RHPubMed
TargetCasein kinase I isoform alpha/delta/epsilon/gamma-1/gamma-2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50229971(4-(4-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-5-pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of human CK1 in presence of [gamma33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4FJBPubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50229971(4-(4-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-5-pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 171nMAssay Description:Inhibition of human CK1D using KRRRAL[pS]VASLPGL as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W380MTPubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50229971(4-(4-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-5-pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of PKD1 in the presence of 50uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27082B4PubMed