null
SMILES Cc1nn2c(O)cc(nc2c1-c1ccc(Cl)cc1)C1CCN(CC1)C(=O)OCc1ccccc1
InChI Key InChIKey=AAUMHOWAFCZIFJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50239160
TargetShort transient receptor potential channel 6(Mus musculus)
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (MOE) and Hubei Provinc
Curated by ChEMBL
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (MOE) and Hubei Provinc
Curated by ChEMBL
Affinity DataEC50: 2.05E+3nMAssay Description:Agonist activity at mouse TRPC6 expressed in HEK293 cells co-expressing Gq11-PLCbeta fused M5 receptor assessed as peak current changes at +80 mV by ...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (MOE) and Hubei Provinc
Curated by ChEMBL
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (MOE) and Hubei Provinc
Curated by ChEMBL
Affinity DataEC50: 138nMAssay Description:Agonist activity at human TRPC3 expressed in HEK293 cells assessed as induction of membrane depolarization measured for 2.5 mins in presence of 0.5 m...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 6(Mus musculus)
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (MOE) and Hubei Provinc
Curated by ChEMBL
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (MOE) and Hubei Provinc
Curated by ChEMBL
Affinity DataEC50: 7.79E+3nMAssay Description:Agonist activity at mouse TRPC6 expressed in HEK293 cells co-expressing Gq11-PLCbeta fused M5 receptor assessed as increase in intracellular calcium ...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 7(Homo sapiens)
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (MOE) and Hubei Provinc
Curated by ChEMBL
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (MOE) and Hubei Provinc
Curated by ChEMBL
Affinity DataEC50: 213nMAssay Description:Agonist activity at human TRPC7 expressed in HEK293 cells assessed as increase in intracellular calcium level measured for 2.5 mins in presence of 2 ...More data for this Ligand-Target Pair