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SMILES Cc1c(s\c(=N/S(=O)(=O)c2cccc(c2)[N+]([O-])=O)n1C)C(C)(C)C

InChI Key InChIKey=DVJYFYQACAKCOT-PEZBUJJGSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 5026   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Yamanouchi Pharmaceutical Co. Ltd

LigandPNGBDBM5026(3-substituted thiazolidene deriv. 17a | N-[(2Z)-5-...)copy SMILEScopy InChI
Affinity DataIC50: 270nMpH: 8.4 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53J1ZPubMed
TargetGag-Pol polyprotein [588-1027,K690N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Yamanouchi Pharmaceutical Co. Ltd

LigandPNGBDBM5026(3-substituted thiazolidene deriv. 17a | N-[(2Z)-5-...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+4nMpH: 8.4 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53J1ZPubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Yamanouchi Pharmaceutical Co. Ltd

LigandPNGBDBM5026(3-substituted thiazolidene deriv. 17a | N-[(2Z)-5-...)copy SMILEScopy InChI
Affinity DataIC50: 66nMpH: 8.4 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53J1ZPubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM5026(3-substituted thiazolidene deriv. 17a | N-[(2Z)-5-...)copy SMILEScopy InChI
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by HeLa-MAGI assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0XPKPubMed
TargetGag-Pol polyprotein [588-1027,K690N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Yamanouchi Pharmaceutical Co. Ltd

LigandPNGBDBM5026(3-substituted thiazolidene deriv. 17a | N-[(2Z)-5-...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+4nMpH: 8.4 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0R24PubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Yamanouchi Pharmaceutical Co. Ltd

LigandPNGBDBM5026(3-substituted thiazolidene deriv. 17a | N-[(2Z)-5-...)copy SMILEScopy InChI
Affinity DataIC50: 66nMpH: 8.4 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0R24PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM5026(3-substituted thiazolidene deriv. 17a | N-[(2Z)-5-...)copy SMILEScopy InChI
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by HeLa-MAGI assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0XPKPubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Yamanouchi Pharmaceutical Co. Ltd

LigandPNGBDBM5026(3-substituted thiazolidene deriv. 17a | N-[(2Z)-5-...)copy SMILEScopy InChI
Affinity DataIC50: 270nMpH: 8.4 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0R24PubMed