null

SMILES CNc1ncc2CN(C(=O)N(C3CCN(CC3)C(=O)\C=C\CN(C)C)c2n1)c1c(Cl)c(OC)cc(OC)c1Cl

InChI Key InChIKey=NMFMLTFZEUDACF-VOTSOKGWSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50260193   

TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Guangzhou Institutes of Biomedicine and Health

Curated by ChEMBL
LigandPNGBDBM50260193(CHEMBL4092354)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human recombinant cytoplasmic His-tagged FGFR2 (403 to 822 residues) expressed in baculovirus using Tyr-4 peptide after 1 hr by FRET-ba...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K076QFPubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Guangzhou Institutes of Biomedicine and Health

Curated by ChEMBL
LigandPNGBDBM50260193(CHEMBL4092354)copy SMILEScopy InChI
Affinity DataIC50: 7.60nMAssay Description:Inhibition of human recombinant His-tagged FGFR3 cytoplasmic domain (399 to 806 residues) expressed in baculovirus using Tyr-4 peptide after 1 hr by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K076QFPubMed
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Guangzhou Institutes of Biomedicine and Health

Curated by ChEMBL
LigandPNGBDBM50260193(CHEMBL4092354)copy SMILEScopy InChI
Affinity DataIC50: 452nMAssay Description:Inhibition of human recombinant His-tagged FGFR4 cytoplasmic domain (781 to 1338 residues) expressed in baculovirus using Tyr-4 peptide after 1 hr by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K076QFPubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Guangzhou Institutes of Biomedicine and Health

Curated by ChEMBL
LigandPNGBDBM50260193(CHEMBL4092354)copy SMILEScopy InChI
Affinity DataIC50: 0.730nMAssay Description:Inhibition of human recombinant His-tagged FGFR1 cytoplasmic domain (308 to 731 residues) expressed in baculovirus using Tyr-4 peptide after 1 hr by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K076QFPubMed