null

SMILES CC(C)N(C)C(=O)N1CCC(=CC1)c1nnn(c1C)-c1cccnc1F

InChI Key InChIKey=CJTLKLBSIFQKNT-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50273942   

TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50273942(4-(1-(2-fluoropyridin-3-yl)-5-methyl-1H-1,2,3-tria...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Binding affinity to mGluR1 by PET analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2Q9BPubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50273942(4-(1-(2-fluoropyridin-3-yl)-5-methyl-1H-1,2,3-tria...)copy SMILEScopy InChI
Affinity DataKi:  3.90nMAssay Description:Binding affinity to mGluR1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6QSSPubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50273942(4-(1-(2-fluoropyridin-3-yl)-5-methyl-1H-1,2,3-tria...)copy SMILEScopy InChI
Affinity DataIC50: 5.60nMAssay Description:Antagonist activity at human mGluR1 receptor expressed in CHO cell membranes assessed as inhibition of L-glutamate-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HGNPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50273942(4-(1-(2-fluoropyridin-3-yl)-5-methyl-1H-1,2,3-tria...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human mGluR5 receptor expressed in CHO cell membranes assessed as inhibition of L-glutamate-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HGNPubMed
TargetMetabotropic glutamate receptor 1(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50273942(4-(1-(2-fluoropyridin-3-yl)-5-methyl-1H-1,2,3-tria...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Antagonist activity at mouse mGluR1 expressed in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN66K2PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50273942(4-(1-(2-fluoropyridin-3-yl)-5-methyl-1H-1,2,3-tria...)copy SMILEScopy InChI
Affinity DataIC50: 6.20E+3nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN66K2PubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50273942(4-(1-(2-fluoropyridin-3-yl)-5-methyl-1H-1,2,3-tria...)copy SMILEScopy InChI
Affinity DataIC50: 5.80nMAssay Description:Antagonist activity at human mGluR1 expressed in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN66K2PubMed