null
SMILES [H][C@@]12CCCC[C@]1([H])N(CCN2C(=O)c1ccco1)c1nc(N)c2cc(OC)c(OC)cc2n1
InChI Key InChIKey=XBRXTUGRUXGBPX-SJORKVTESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 50274049
Affinity DataKi: 0.0603nMAssay Description:Displacement of [3H]prazosin from human alpha1D adrenergic receptor expressed in CHO cell membranes after 30 mins by rapid filtration methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.0708nMAssay Description:Displacement of [3H]prazosin from human alpha1B adrenergic receptor expressed in CHO cell membranes after 30 mins by rapid filtration methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.135nMAssay Description:Compound was tested for binding affinity against human hippocampus Alpha-1B adrenergic receptor using radioligand ([3H]-prazosin) binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.209nMAssay Description:Compound was tested for binding affinity against native Alpha-1B adrenergic receptor from rat liver using radioligand ([3H]prazosin) binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.589nMAssay Description:Displacement of [3H]prazosin from human alpha1A adrenergic receptor expressed in CHO cell membranes after 30 mins by rapid filtration methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.692nMAssay Description:Compound was tested for binding affinity against cloned Alpha-1B adrenergic receptor from hamster smooth muscle using radioligand ([3H]prazosin) bind...More data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Compound was tested for binding affinity against human hippocampus Alpha-1D adrenergic receptor using radioligand ([3H]prazosin) binding assayMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
University of Camerino
Curated by ChEMBL
University of Camerino
Curated by ChEMBL
Affinity DataKi: 5.20nMAssay Description:Binding affinity against native Alpha-1 adrenergic receptor from rat cerebral cortex using radioligand [3H]-prazosin binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Compound was tested for binding affinity against human hippocampus Alpha-1A adrenergic receptor using radioligand ([3H]prazosin) binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Binding affinity against native Alpha-1A adrenergic receptor from rat hippocampus pretreated with chloroethylclonidine using radioligand ([3H]prazosi...More data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Compound was tested for binding affinity against cloned Alpha-1D adrenergic receptor from rat brain using radioligand ([3H]prazosin) binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Compound was tested for binding affinity against cloned Alpha-1A adrenergic receptor from bovine brain using radioligand ([3H]prazosin) binding assayMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
University of Camerino
Curated by ChEMBL
University of Camerino
Curated by ChEMBL
Affinity DataKi: 741nMAssay Description:Binding affinity against native Alpha-2 adrenergic receptor from rat cerebral cortex using radioligand ([3H]rauwolscine) binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 8.32E+3nMAssay Description:Compound was tested for binding affinity against native Dopamine receptor D2 from rat striatum using radioligand [3H]-spiperone)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University of Camerino
Curated by ChEMBL
University of Camerino
Curated by ChEMBL
Affinity DataKi: 1.29E+4nMAssay Description:Binding affinity against native 5-HT1A-receptors from rat hippocampus using radioligand ([3H]8-hydroxy-2-(di-n-propylamino)-tetraline) binding assayMore data for this Ligand-Target Pair