null

SMILES CN(Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(=O)c1c(N2CCCC2)c2ccccc2n(C)c1=O

InChI Key InChIKey=MCDADOMPEINVRO-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50282210   

TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50282210(CHEMBL4162182)copy SMILEScopy InChI
Affinity DataIC50: 410nMAssay Description:Inhibition of human SMS2 expressed in HEK293T cells using C2-ceramide as substrate preincubated for 60 mins followed by substrate addition measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5QB9PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50282210(CHEMBL4162182)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human SMS1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5QB9PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50282210(CHEMBL4162182)copy SMILEScopy InChI
Affinity DataIC50: 950nMAssay Description:Inhibition of human SMS2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5QB9PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50282210(CHEMBL4162182)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant C-terminal FLAG-tagged SMS1 expressed in mammalian expression system using C14-phosphatidylcholineD72 and C17-ceramid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J106QTPubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50282210(CHEMBL4162182)copy SMILEScopy InChI
Affinity DataIC50: 470nMAssay Description:Compound was evaluated for the inhibition of thymidylate synthase obtained from humanMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5QB9PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50282210(CHEMBL4162182)copy SMILEScopy InChI
Affinity DataIC50: 950nMAssay Description:Inhibition of human recombinant C-terminal FLAG-tagged SMS2 expressed in Freestyle293 cell membrane using C14-phosphatidylcholineD72 and C17-ceramide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J106QTPubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Mus musculus)
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50282210(CHEMBL4162182)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of mouse recombinant C-terminal FLAG-tagged SMS2 expressed in mammalian expression system using C14-phosphatidylcholineD72 and C17-ceramid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J106QTPubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50282210(CHEMBL4162182)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMAssay Description:Compound was evaluated for the inhibition of glycinamide ribonucleotide transformylase obtained from porcine (GAR Tfase)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5QB9PubMed