null

SMILES COc1cc2CC[n+]3cc4c(OC)c(OC)ccc4cc3-c2cc1OC

InChI Key InChIKey=QUCQEUCGKKTEBI-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50292332   

TargetNeuraminidase(Influenza A virus (strain A/USSR/90/1977 H1N1))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50292332(2,3,9,10-Tetramethoxy-5,6-dihydro-isoquino[3,2-a]i...)copy SMILEScopy InChI
Affinity DataIC50: 3.31E+4nMAssay Description:Inhibition of recombinant Influenza A virus H1N1 neuraminidase using 4-methylumbelliferyl-alpha-D-Nacetylneuraminic acid sodium salt hydrate as subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q269755JPubMed
TargetNeuraminidase(Influenza A virus (strain A/USSR/90/1977 H1N1))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50292332(2,3,9,10-Tetramethoxy-5,6-dihydro-isoquino[3,2-a]i...)copy SMILEScopy InChI
Affinity DataIC50: 2.98E+4nMAssay Description:Inhibition of Influenza A virus H5N1 neuraminidase using 4-methylumbelliferyl-alpha-D-Nacetylneuraminic acid sodium salt hydrate as substrate by fluo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q269755JPubMed
TargetGenome polyprotein(West Nile virus)
University of KwaZulu-Natal

Curated by ChEMBL
LigandPNGBDBM50292332(2,3,9,10-Tetramethoxy-5,6-dihydro-isoquino[3,2-a]i...)copy SMILEScopy InChI
Affinity DataIC50: 9.60E+4nMAssay Description:Non-competitive inhibition of West Nile virus NS2B-NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K9CPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50292332(2,3,9,10-Tetramethoxy-5,6-dihydro-isoquino[3,2-a]i...)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli assessed as inhibition of nifedipine oxidationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3KX1PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Abo Akademi University

Curated by ChEMBL
LigandPNGBDBM50292332(2,3,9,10-Tetramethoxy-5,6-dihydro-isoquino[3,2-a]i...)copy SMILEScopy InChI
Affinity DataIC50: 1.69E+3nMAssay Description:Inhibition of human AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6TBTPubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Abo Akademi University

Curated by ChEMBL
LigandPNGBDBM50292332(2,3,9,10-Tetramethoxy-5,6-dihydro-isoquino[3,2-a]i...)copy SMILEScopy InChI
Affinity DataIC50: 4.07E+3nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6TBTPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50292332(2,3,9,10-Tetramethoxy-5,6-dihydro-isoquino[3,2-a]i...)copy SMILEScopy InChI
Affinity DataIC50: 1.22E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19G8PubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Abo Akademi University

Curated by ChEMBL
LigandPNGBDBM50292332(2,3,9,10-Tetramethoxy-5,6-dihydro-isoquino[3,2-a]i...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6M22PubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Charles University

Curated by ChEMBL
LigandPNGBDBM50292332(2,3,9,10-Tetramethoxy-5,6-dihydro-isoquino[3,2-a]i...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of POP (unknown origin) using (Z)-Gly-Pro-p-nitroanilide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8BXFPubMed
TargetCholinesterase(Homo sapiens (Human))
Charles University

Curated by ChEMBL
LigandPNGBDBM50292332(2,3,9,10-Tetramethoxy-5,6-dihydro-isoquino[3,2-a]i...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate measured for 1 min by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8BXFPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Abo Akademi University

Curated by ChEMBL
LigandPNGBDBM50292332(2,3,9,10-Tetramethoxy-5,6-dihydro-isoquino[3,2-a]i...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate measured for 1 min by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8BXFPubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))TBA
LigandPNGBDBM50292332(2,3,9,10-Tetramethoxy-5,6-dihydro-isoquino[3,2-a]i...)copy SMILEScopy InChI
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of N-terminal His/GST-tagged human p300 HAT (965 to 1810 residues) expressed in Sf9 insect cells using H3 peptide as substrate in presence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC14D7PubMed
TargetSnake venom metalloproteinase BaP1(Bothrops asper)
TBA

Curated by ChEMBL
LigandPNGBDBM50292332(2,3,9,10-Tetramethoxy-5,6-dihydro-isoquino[3,2-a]i...)copy SMILEScopy InChI
Affinity DataIC50: 9.33E+4nMAssay Description:Inhibition of snake venom BaP1 using Abz-Ala-Gly-Leu-Ala-Nba as substrate incubated for 30 mins prior to substrate addition by fluorescence spectroph...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542PVSPubMed