null

SMILES CSc1ccc(Nc2nc3cc(ccc3n2Cc2ccccc2C(F)(F)F)C(N)=O)cc1

InChI Key InChIKey=LDIUIXFIAWISPB-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50293756   

TargetKinesin-like protein KIF11(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM50293756(2-(4-(methylthio)phenylamino)-1-(2-(trifluoromethy...)copy SMILEScopy InChI
Affinity DataKd:  2.00E+3nMAssay Description:Binding assay using temperature-dependent circular dichroism (TdCD). In TdCD, the loss of protein secondary structure was monitored as a function of...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2DQ0PubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM50293756(2-(4-(methylthio)phenylamino)-1-(2-(trifluoromethy...)copy SMILEScopy InChI
Affinity DataIC50: 520nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3SS3PubMed
TargetKinesin-like protein KIF3B(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293756(2-(4-(methylthio)phenylamino)-1-(2-(trifluoromethy...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Kif3BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3SS3PubMed
TargetKinesin heavy chain isoform 5A(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293756(2-(4-(methylthio)phenylamino)-1-(2-(trifluoromethy...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of nKHCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3SS3PubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293756(2-(4-(methylthio)phenylamino)-1-(2-(trifluoromethy...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CYP2C9 preincubated with compoundMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3SS3PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293756(2-(4-(methylthio)phenylamino)-1-(2-(trifluoromethy...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 coincubated with compoundMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3SS3PubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293756(2-(4-(methylthio)phenylamino)-1-(2-(trifluoromethy...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of CYP2C9 coincubated with compoundMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3SS3PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293756(2-(4-(methylthio)phenylamino)-1-(2-(trifluoromethy...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of CYP2D6 preincubated with compoundMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3SS3PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293756(2-(4-(methylthio)phenylamino)-1-(2-(trifluoromethy...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4 coincubated with compoundMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3SS3PubMed