null

SMILES CN1C(N)=NC(C2CCCCC2)(C1=O)c1cccc(NC(=O)c2occc2C)c1

InChI Key InChIKey=CZSNUKITORTJBZ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50305469   

TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305469(CHEMBL590830 | N-(3-(2-amino-4-cyclohexyl-1-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z73BNPubMed
TargetCathepsin D(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305469(CHEMBL590830 | N-(3-(2-amino-4-cyclohexyl-1-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.71E+4nMAssay Description:Inhibition of human cathepsin D by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z73BNPubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305469(CHEMBL590830 | N-(3-(2-amino-4-cyclohexyl-1-methyl...)copy SMILEScopy InChI
Affinity DataEC50:  180nMAssay Description:Inhibition of human recombinant APP expressed in CHO-K1 cells assessed as reduction of amyloid beta level by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z73BNPubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305469(CHEMBL590830 | N-(3-(2-amino-4-cyclohexyl-1-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human BACE2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z73BNPubMed