null

SMILES Cc1n(Cc2cccnc2)c(=O)cc2[nH]n(-c3ccccc3)c(=O)c12

InChI Key InChIKey=ISLQXEIRVZXLJA-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50330688   

TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex, S.A.

Curated by ChEMBL
LigandPNGBDBM50330688(4-methyl-2-phenyl-5-(pyridin-3-ylmethyl)-1H-pyrazo...)copy SMILEScopy InChI
Affinity DataKi:  373nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NKJPubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
Genkyotex, S.A.

Curated by ChEMBL
LigandPNGBDBM50330688(4-methyl-2-phenyl-5-(pyridin-3-ylmethyl)-1H-pyrazo...)copy SMILEScopy InChI
Affinity DataKi:  4.72E+3nMAssay Description:Inhibition of human NOX2 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NKJPubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Genkyotex, S.A.

Curated by ChEMBL
LigandPNGBDBM50330688(4-methyl-2-phenyl-5-(pyridin-3-ylmethyl)-1H-pyrazo...)copy SMILEScopy InChI
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of xanthine oxidase by invitro enzymatic assay in presence of xanthineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NKJPubMed