null

SMILES CC(C)[C@H]1N(CC(=O)N(O)C1=O)S(=O)(=O)c1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=RQCBSNJRFVZHOS-GOSISDBHSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50361601   

TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Instituto Superior T£cnico

Curated by ChEMBL
LigandPNGBDBM50361601(CHEMBL1939846)copy SMILEScopy InChI
Affinity DataIC50: 83nMAssay Description:Inhibition of human recombinant MMP14 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53QNPubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Instituto Superior T£cnico

Curated by ChEMBL
LigandPNGBDBM50361601(CHEMBL1939846)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant MMP9 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53QNPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Instituto Superior T£cnico

Curated by ChEMBL
LigandPNGBDBM50361601(CHEMBL1939846)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of MMP1 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs for 20 mins by fluor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53QNPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Instituto Superior T£cnico

Curated by ChEMBL
LigandPNGBDBM50361601(CHEMBL1939846)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant MMP2 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53QNPubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Instituto Superior T£cnico

Curated by ChEMBL
LigandPNGBDBM50361601(CHEMBL1939846)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TACE using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs for 20 mins by fluor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53QNPubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Instituto Superior T£cnico

Curated by ChEMBL
LigandPNGBDBM50361601(CHEMBL1939846)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant MMP8 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53QNPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Instituto Superior T£cnico

Curated by ChEMBL
LigandPNGBDBM50361601(CHEMBL1939846)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of MMP12 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs for 20 mins by fluo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53QNPubMed
TargetCollagenase 3(Homo sapiens (Human))
Instituto Superior T£cnico

Curated by ChEMBL
LigandPNGBDBM50361601(CHEMBL1939846)copy SMILEScopy InChI
Affinity DataIC50: 9.5nMAssay Description:Inhibition of MMP13 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs for 20 mins by fluo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53QNPubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior T£cnico

Curated by ChEMBL
LigandPNGBDBM50361601(CHEMBL1939846)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of human recombinant MMP16 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53QNPubMed
TargetStromelysin-1(Homo sapiens (Human))
Instituto Superior T£cnico

Curated by ChEMBL
LigandPNGBDBM50361601(CHEMBL1939846)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of MMP3 using Mca-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 as substrate preincubated for 4 hrs measured every 15 secs for 20 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53QNPubMed