null
SMILES OC(=O)CSc1cc(NS(=O)(=O)c2ccc(cc2)C(O)=O)c2ccccc2c1O
InChI Key InChIKey=CIERPRDYPKVDJO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50396170
TargetHistone acetyltransferase GCN5(Saccharomyces cerevisiae S288c)
Mayo Clinic College of Medicine
Curated by ChEMBL
Mayo Clinic College of Medicine
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of Vps75-stimulated recombinant Saccharomyces cerevisiae histone acetyltransferase Rtt109 using [3H]-acetyl-CoA assessed as acetate incorp...More data for this Ligand-Target Pair
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Mayo Clinic College of Medicine
Curated by ChEMBL
Mayo Clinic College of Medicine
Curated by ChEMBL
Affinity DataIC50: 660nMAssay Description:Inhibition of recombinant histone acetyltransferase p300 (unknown origin) using dH3-H4 tetramer and [3H]-acetyl-CoA assessed as acetate incorporation...More data for this Ligand-Target Pair
TargetHistone acetyltransferase GCN5(Saccharomyces cerevisiae S288c)
Mayo Clinic College of Medicine
Curated by ChEMBL
Mayo Clinic College of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of yeast histone acetyltransferase Gcn5-Ada2-Ada3 complex using tetramer and [3H]-acetyl-CoA assessed as acetate incorporation after 30 mi...More data for this Ligand-Target Pair
In DepthDetails
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant STAT3 assessed as inhibition of STAT3-phosphododecapeptide interaction by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails
In DepthDetails
Affinity DataIC50: 7.30E+4nMAssay Description:Inhibition of IL6-mediated STAT3 phosphorylation in human HepG2 cells preincubated for 1 hr prior to IL6 challenge measured after 30 mins by immunobl...More data for this Ligand-Target Pair