null
SMILES CCN(CC)CCCCNc1ncc2CN(C(=O)N(Cc3cccc(NC(=O)C=C)c3)c2n1)c1c(Cl)c(OC)cc(OC)c1Cl
InChI Key InChIKey=DNVFTXQYIYFQBW-UHFFFAOYSA-N
PDB links: 1 PDB ID matches this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 17 hits for monomerid = 50403060
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Covalution Pharma BV
Curated by ChEMBL
Covalution Pharma BV
Curated by ChEMBL
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Covalution Pharma BV
Curated by ChEMBL
Covalution Pharma BV
Curated by ChEMBL
In DepthDetails
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Covalution Pharma BV
Curated by ChEMBL
Covalution Pharma BV
Curated by ChEMBL
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Covalution Pharma BV
Curated by ChEMBL
Covalution Pharma BV
Curated by ChEMBL
Affinity DataIC50: 9.20nMAssay Description:Inhibition of recombinant FGFR1More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Covalution Pharma BV
Curated by ChEMBL
Covalution Pharma BV
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibition of His-tagged cytoplasmic recombinant human FGFR2 (403 to 822 residues) expressed in baculovirus expression system using Tyr 4 peptide as ...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Chinese Academy of Sciences
Curated by ChEMBL
Chinese Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of His-tagged cytoplasmic recombinant human FGFR3 (399 to 806 residues) expressed in baculovirus expression system using Tyr 4 peptide as ...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Covalution Pharma BV
Curated by ChEMBL
Covalution Pharma BV
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Inhibition of His-tagged cytoplasmic recombinant human FGFR1 (308 to 731 residues) expressed in baculovirus expression system using Tyr 4 peptide as ...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Covalution Pharma BV
Curated by ChEMBL
Covalution Pharma BV
Curated by ChEMBL
Affinity DataIC50: 261nMAssay Description:Inhibition of His-tagged cytoplasmic recombinant human FGFR4 (781 to 1338 residues) expressed in baculovirus expression system using Tyr 4 peptide as...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Covalution Pharma BV
Curated by ChEMBL
Covalution Pharma BV
Curated by ChEMBL
Affinity DataIC50: 261nMAssay Description:Inhibition of human recombinant His-tagged FGFR4 cytoplasmic domain (781 to 1338 residues) expressed in baculovirus using Tyr-4 peptide after 1 hr by...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Chinese Academy of Sciences
Curated by ChEMBL
Chinese Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant His-tagged FGFR3 cytoplasmic domain (399 to 806 residues) expressed in baculovirus using Tyr-4 peptide after 1 hr by ...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Covalution Pharma BV
Curated by ChEMBL
Covalution Pharma BV
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human recombinant cytoplasmic His-tagged FGFR2 (403 to 822 residues) expressed in baculovirus using Tyr-4 peptide after 1 hr by FRET-ba...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Covalution Pharma BV
Curated by ChEMBL
Covalution Pharma BV
Curated by ChEMBL
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human recombinant His-tagged FGFR1 cytoplasmic domain (308 to 731 residues) expressed in baculovirus using Tyr-4 peptide after 1 hr by ...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Covalution Pharma BV
Curated by ChEMBL
Covalution Pharma BV
Curated by ChEMBL
Affinity DataEC50: 14nMAssay Description:Inhibition of Tel-fused FGFR1 (unknown origin) expressed in mouse Ba/F3 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assayMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Covalution Pharma BV
Curated by ChEMBL
Covalution Pharma BV
Curated by ChEMBL
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Covalution Pharma BV
Curated by ChEMBL
Covalution Pharma BV
Curated by ChEMBL
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Chinese Academy of Sciences
Curated by ChEMBL
Chinese Academy of Sciences
Curated by ChEMBL
In DepthDetails
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Chinese Academy of Sciences
Curated by ChEMBL
Chinese Academy of Sciences
Curated by ChEMBL