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SMILES FC(F)(F)c1c(CCc2ccccc2)n2CCOc3cccc1c23

InChI Key InChIKey=FZBIFJDVJQDOQI-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50443625   

TargetEndothelial lipase(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM50443625(CHEMBL3092448 | US9216998, 25)copy SMILEScopy InChI
Affinity DataIC50: 39nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22N513FUS Patent
TargetEndothelial lipase(Mus musculus (Mouse))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM50443625(CHEMBL3092448 | US9216998, 25)copy SMILEScopy InChI
Affinity DataIC50: 31nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22N513FUS Patent
TargetEndothelial lipase(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM50443625(CHEMBL3092448 | US9216998, 25)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of endothelial lipase in human cells after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5C4QPubMed
TargetEndothelial lipase(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM50443625(CHEMBL3092448 | US9216998, 25)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of human endothelial lipase using PLAi as substrate measured for 30 mins by cell-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6DBGPubMed
TargetEndothelial lipase(Mus musculus (Mouse))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM50443625(CHEMBL3092448 | US9216998, 25)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of endothelial lipase in mouse cells after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5C4QPubMed
TargetEndothelial lipase(Mus musculus (Mouse))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM50443625(CHEMBL3092448 | US9216998, 25)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of mouse endothelial lipase using PLAi as substrate measured for 30 mins by cell-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6DBGPubMed