null

SMILES C[C@H]1COCCN1C[C@H]1CN(CCN1c1ccc(cc1)[C@@](C)(O)C(F)(F)F)S(=O)(=O)c1cccs1

InChI Key InChIKey=OJTJLEFGCNYTBQ-RBDMOPTHSA-N

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50447292   

TargetHexokinase-4(Mus musculus (Mouse))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50447292(CHEMBL3113979)copy SMILEScopy InChI
Affinity DataEC50:  1.79E+3nMAssay Description:Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q241Q5PubMed
TargetGlucokinase regulatory protein(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50447292(CHEMBL3113979)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of biotin-tagged human GKRP-fluorescein-tagged human GK interaction preincubated for 20 mins followed by fluorescein-tagged human GK addit...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50447292(CHEMBL3113979)copy SMILEScopy InChI
Affinity DataEC50: >5.00E+4nMAssay Description:Activation of human glucokinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5HJ4PubMed
TargetGlucokinase regulatory protein(Rattus norvegicus)
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50447292(CHEMBL3113979)copy SMILEScopy InChI
Affinity DataEC50:  82nMAssay Description:Inhibition of GKRP-GK interaction in rat primary hepatocytes assessed as translocation of GK from nucleus to cytoplasm preincubated for 20 mins follo...More data for this Ligand-Target Pair