null
SMILES CNc1cc(ccn1)-c1ccc(s1)C(=O)Nc1nc2ccccc2n1[C@H]1C[C@]2(C1)CCN(C2)C(=O)C=C
InChI Key InChIKey=QPIYIWYNEVEBBY-LBLBPIOVSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50458588
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Temple University School of Pharmacy
Curated by ChEMBL
Temple University School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 0.410nMAssay Description:Inhibition of ITK (unknown origin) using fluorescently labeled peptide as substrate after 3 hrs by microfluidic mobility shift assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
Temple University School of Pharmacy
Curated by ChEMBL
Temple University School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 0.180nMAssay Description:Inhibition of TXK (unknown origin) using fluorescently labeled peptide as substrate after 3 hrs by microfluidic mobility shift assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Temple University School of Pharmacy
Curated by ChEMBL
Temple University School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 0.460nMAssay Description:Inhibition of BTK (unknown origin) using fluorescently labeled peptide as substrate after 3 hrs by microfluidic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Temple University School of Pharmacy
Curated by ChEMBL
Temple University School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 0.410nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
Temple University School of Pharmacy
Curated by ChEMBL
Temple University School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 0.180nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Temple University School of Pharmacy
Curated by ChEMBL
Temple University School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 0.460nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:Inhibition of TEC (unknown origin) using fluorescently labeled peptide as substrate after 3 hrs by microfluidic mobility shift assayMore data for this Ligand-Target Pair