null

SMILES CC(F)(F)c1ccc(s1)C(=O)Nc1nc2ccccc2n1[C@H]1C[C@]2(C1)CCN(C2)C(=O)C=C

InChI Key InChIKey=CYGPGKKCJOVFQJ-AOVWKMQPSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50458593   

TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Temple University School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50458593(CHEMBL4204572 | US10752615, Compound 30)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Inhibition of ITK (unknown origin) using fluorescently labeled peptide as substrate after 3 hrs by microfluidic mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2JQNPubMed
TargetTyrosine-protein kinase Tec(Homo sapiens (Human))
Temple University School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50458593(CHEMBL4204572 | US10752615, Compound 30)copy SMILEScopy InChI
Affinity DataIC50: 0.980nMAssay Description:Inhibition of TEC (unknown origin) using fluorescently labeled peptide as substrate after 3 hrs by microfluidic mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2JQNPubMed
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
Temple University School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50458593(CHEMBL4204572 | US10752615, Compound 30)copy SMILEScopy InChI
Affinity DataIC50: 0.290nMAssay Description:Inhibition of TXK (unknown origin) using fluorescently labeled peptide as substrate after 3 hrs by microfluidic mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2JQNPubMed
TargetTyrosine-protein kinase Tec(Homo sapiens (Human))
Temple University School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50458593(CHEMBL4204572 | US10752615, Compound 30)copy SMILEScopy InChI
Affinity DataIC50: 0.980nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Temple University School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50458593(CHEMBL4204572 | US10752615, Compound 30)copy SMILEScopy InChI
Affinity DataIC50: 2.17nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
Temple University School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50458593(CHEMBL4204572 | US10752615, Compound 30)copy SMILEScopy InChI
Affinity DataIC50: 0.290nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM50458593(CHEMBL4204572 | US10752615, Compound 30)copy SMILEScopy InChI
Affinity DataIC50: 2.11nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM50458593(CHEMBL4204572 | US10752615, Compound 30)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Inhibition of BTK (unknown origin) using fluorescently labeled peptide as substrate after 3 hrs by microfluidic mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2JQNPubMed