null
SMILES CC(F)(F)c1ccc(s1)C(=O)Nc1nc2ccccc2n1[C@H]1C[C@]2(C1)CCN(C2)C(=O)C=C
InChI Key InChIKey=CYGPGKKCJOVFQJ-AOVWKMQPSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50458593
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Temple University School of Pharmacy
Curated by ChEMBL
Temple University School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of ITK (unknown origin) using fluorescently labeled peptide as substrate after 3 hrs by microfluidic mobility shift assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Tec(Homo sapiens (Human))
Temple University School of Pharmacy
Curated by ChEMBL
Temple University School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 0.980nMAssay Description:Inhibition of TEC (unknown origin) using fluorescently labeled peptide as substrate after 3 hrs by microfluidic mobility shift assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
Temple University School of Pharmacy
Curated by ChEMBL
Temple University School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 0.290nMAssay Description:Inhibition of TXK (unknown origin) using fluorescently labeled peptide as substrate after 3 hrs by microfluidic mobility shift assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Tec(Homo sapiens (Human))
Temple University School of Pharmacy
Curated by ChEMBL
Temple University School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 0.980nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Temple University School of Pharmacy
Curated by ChEMBL
Temple University School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 2.17nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
Temple University School of Pharmacy
Curated by ChEMBL
Temple University School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 0.290nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Affinity DataIC50: 2.11nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of BTK (unknown origin) using fluorescently labeled peptide as substrate after 3 hrs by microfluidic mobility shift assayMore data for this Ligand-Target Pair