null

SMILES C[C@](O)(c1ccnc(c1)-c1cccc2cc(sc12)[C@H](NS(=O)(=O)C1CC1)c1ccccc1Cl)C(F)(F)F

InChI Key InChIKey=MBAGUBQPZLMGBR-NOZRDPDXSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50500199   

TargetGlucokinase regulatory protein(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50500199(CHEMBL3747490)copy SMILEScopy InChI
Affinity DataKd:  250nMAssay Description:Binding affinity to human GKRP by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0BZPPubMed
TargetGlucokinase regulatory protein(Rattus norvegicus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50500199(CHEMBL3747490)copy SMILEScopy InChI
Affinity DataKd:  800nMAssay Description:Binding affinity to rat GKRP by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0BZPPubMed
TargetGlucokinase regulatory protein(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50500199(CHEMBL3747490)copy SMILEScopy InChI
Affinity DataEC50: >1.25E+4nMAssay Description:Inhibition of glucokinase-GKRP binding interaction in mouse hepatocytes assessed as induction of glucokinase translocationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0BZPPubMed
TargetGlucokinase regulatory protein(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50500199(CHEMBL3747490)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Binding affinity to human biotinylated AviTag GKRP assessed as inhibition of protein interaction with fluorescein tagged human glucokinase by AlphaSc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0BZPPubMed
TargetGlucokinase regulatory protein(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50500199(CHEMBL3747490)copy SMILEScopy InChI
Affinity DataKd:  850nMAssay Description:Binding affinity to mouse GKRP by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0BZPPubMed