null
SMILES COC1(CC(C)(C)C(=O)C(=C1)C#N)c1ncccc1C(F)(F)F
InChI Key InChIKey=DFYZORBOTKVKRC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50502724
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Temple University School of Pharmacy
Curated by ChEMBL
Temple University School of Pharmacy
Curated by ChEMBL
Affinity DataEC50: 24nMAssay Description:Inhibition of KEAP1 interaction with Nrf2 in human HEK293 cells transfected with ARE-LUC assessed as activation of Nrf2 signaling pathway measured af...More data for this Ligand-Target Pair
Affinity DataEC50: 24nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
Affinity DataEC50: 43nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair