null

SMILES COc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1cc(OCC2CCN(C)CC2)c2ncnc(C)c2c1

InChI Key InChIKey=IGXAFEIHWNLFBZ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50505309   

TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha(Homo sapiens (Human))TBA

LigandBDBM50505309(CHEMBL4561621 | US11534443, Example 66)copy SMILEScopy InChI

Affinity DataIC50: 1.70nMAssay Description:The Kinase-Glo™ Kinase Assay Kit was purchased from Promega. All assays were performed at room temperature using white OptiPlate™-384 well plate. The...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails
BindingDB Entry DOI: 10.7270/Q24171WXUS Patent

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50505309(CHEMBL4561621 | US11534443, Example 66)copy SMILEScopy InChI

Affinity DataIC50: 1.60nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged full-length p110alpha/human p85alpha expressed in Sf9 insect cells using PIP2 as substrate by ...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q243JRPubMed