null

SMILES CC(O)(C#Cc1ccc2CCN(c2c1)c1nc(N)ncc1Cl)c1nccs1

InChI Key InChIKey=OKFYOOFXVBCIIP-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50541592   

TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50541592(CHEMBL3187788)copy SMILEScopy InChI
Affinity DataKi:  0.400nMAssay Description:Inhibition of NIK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TGRPubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50541592(CHEMBL3187788)copy SMILEScopy InChI
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0XXDPubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50541592(CHEMBL3187788)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMAssay Description:Inhibition of recombinant N-terminal GST-fused human NIK (319 to 947 residues) expressed in baculovirus expression system incubated for 120 mins in p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TGRPubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50541592(CHEMBL3187788)copy SMILEScopy InChI
Affinity DataIC50: 4.90nMAssay Description:Inhibition of recombinant N-terminal GST-fused human NIK (319 to 947 residues) expressed in baculovirus expression system incubated for 120 mins in p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP49QVPubMed