null

SMILES Fc1cnc(nc1Nc1ccc(cc1)-c1cn[nH]c1)-c1ccc2cc([nH]c2c1)C(=O)N1CC(F)(F)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 561176   

TargetRho-associated protein kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM561176((6-(4-((4-(1H- pyrazol-4- yl)phenyl)amino)-5- fluo...)copy SMILES
Affinity DataIC50: 24nMAssay Description:The kinase IC50 was determined by a commercialized CISBIO kinase detection kit, HTRF KinEASE-STK S2 kit (62ST2PEC). ROCK2 (01-119) employed in the re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20R9SM6US Patent
TargetRho-associated protein kinase 2 [1-119](Homo sapiens (Human))TBA
LigandPNGBDBM561176((6-(4-((4-(1H- pyrazol-4- yl)phenyl)amino)-5- fluo...)copy SMILES
Affinity DataIC50: 24nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F76HPH
TargetRho-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM561176((6-(4-((4-(1H- pyrazol-4- yl)phenyl)amino)-5- fluo...)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:The kinase IC50 was determined by a commercialized CISBIO kinase detection kit, HTRF KinEASE-STK S2 kit (62ST2PEC). ROCK2 (01-119) employed in the re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20R9SM6US Patent