null

SMILES CC(=O)Nc1cc(CCc2cnc(NC(=O)Nc3cc(nn3-c3ccc(C)cc3)C(C)(C)C)s2)ccn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 563619   

TargetMitogen-activated protein kinase 13(Homo sapiens (Human))TBA
LigandPNGBDBM563619(N-[4-[2-[2-[[5-tert-butyl-2-(p- tolyl)pyrazol-3- y...)copy SMILES
Affinity DataIC50: 250nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FN19DPUS Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM563619(N-[4-[2-[2-[[5-tert-butyl-2-(p- tolyl)pyrazol-3- y...)copy SMILES
Affinity DataIC50: 129nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FN19DPUS Patent
TargetMitogen-activated protein kinase 13(Homo sapiens (Human))TBA
LigandPNGBDBM563619(N-[4-[2-[2-[[5-tert-butyl-2-(p- tolyl)pyrazol-3- y...)copy SMILES
Affinity DataIC50: 9nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FN19DPUS Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM563619(N-[4-[2-[2-[[5-tert-butyl-2-(p- tolyl)pyrazol-3- y...)copy SMILES
Affinity DataIC50: 129nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FN19DPUS Patent