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SMILES Clc1cccc(Nc2cncc(n2)-c2cncc(NCCCc3cccnc3)c2)c1

InChI Key InChIKey=IRNVMUQZQDLZAK-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 6419   

TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6419(N-(3-Chlorophenyl)-6-[5-[[3-(3-pyridinyl)propyl]am...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6419(N-(3-Chlorophenyl)-6-[5-[[3-(3-pyridinyl)propyl]am...)copy SMILEScopy InChI
Affinity DataIC50: 76nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6419(N-(3-Chlorophenyl)-6-[5-[[3-(3-pyridinyl)propyl]am...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Oryctolagus cuniculus (rabbit))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6419(N-(3-Chlorophenyl)-6-[5-[[3-(3-pyridinyl)propyl]am...)copy SMILEScopy InChI
Affinity DataIC50: 318nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6419(N-(3-Chlorophenyl)-6-[5-[[3-(3-pyridinyl)propyl]am...)copy SMILEScopy InChI
Affinity DataIC50: 293nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6419(N-(3-Chlorophenyl)-6-[5-[[3-(3-pyridinyl)propyl]am...)copy SMILEScopy InChI
Affinity DataIC50: 876nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed