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SMILES CCOc1ccc2nc(sc2c1)C(=O)ON

InChI Key InChIKey=KYEDSYGQLUWFDF-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 85658   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Università degli Studi di Firenze

LigandPNGBDBM85658(EZA4)copy SMILEScopy InChI
Affinity DataKi:  8nM ΔG°:  -10.9kcal/molepH: 7.4 T: 2°CAssay Description:The initial rates of 4-nitrophenylacetate hydrolysis catalysed by different CA isozymes were monitored spectrophotometrically at 400nm with a Cary 3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4TBBPubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Università degli Studi di Firenze

LigandPNGBDBM85658(EZA4)copy SMILEScopy InChI
Affinity DataKi:  13nM ΔG°:  -10.6kcal/molepH: 7.4 T: 2°CAssay Description:The initial rates of 4-nitrophenylacetate hydrolysis catalysed by different CA isozymes were monitored spectrophotometrically at 400nm with a Cary 3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4TBBPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Università degli Studi di Firenze

LigandPNGBDBM85658(EZA4)copy SMILEScopy InChI
Affinity DataKi:  25nM ΔG°:  -10.2kcal/molepH: 7.4 T: 2°CAssay Description:The initial rates of 4-nitrophenylacetate hydrolysis catalysed by different CA isozymes were monitored spectrophotometrically at 400nm with a Cary 3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4TBBPubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Università degli Studi di Firenze

LigandPNGBDBM85658(EZA4)copy SMILEScopy InChI
Affinity DataKi:  34nM ΔG°:  -10.0kcal/molepH: 7.4 T: 2°CAssay Description:The initial rates of 4-nitrophenylacetate hydrolysis catalysed by different CA isozymes were monitored spectrophotometrically at 400nm with a Cary 3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4TBBPubMed
TargetCarbonic anhydrase 5A, mitochondrial(Mus musculus (mouse))
Università degli Studi di Firenze

LigandPNGBDBM85658(EZA4)copy SMILEScopy InChI
Affinity DataKi:  47nM ΔG°:  -9.82kcal/molepH: 7.4 T: 2°CAssay Description:The initial rates of 4-nitrophenylacetate hydrolysis catalysed by different CA isozymes were monitored spectrophotometrically at 400nm with a Cary 3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4TBBPubMed