null

SMILES N[C@@H](CC(=O)Nc1ccc(Oc2cc(F)c(F)cc2Br)cc1)C(O)=O

InChI Key InChIKey=BNYDDAAZMBUFRG-ZDUSSCGKSA-N

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 86712   

TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM86712(CAS_868359-05-1 | N-[4-(2-BROMO-4,5-DIFLUOROPHENOX...)copy SMILEScopy InChI
Affinity DataKi:  85nMMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM86712(CAS_868359-05-1 | N-[4-(2-BROMO-4,5-DIFLUOROPHENOX...)copy SMILEScopy InChI
Affinity DataKi:  3.79E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NVXPubMed
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM86712(CAS_868359-05-1 | N-[4-(2-BROMO-4,5-DIFLUOROPHENOX...)copy SMILEScopy InChI
Affinity DataKi:  5.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NVXPubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM86712(CAS_868359-05-1 | N-[4-(2-BROMO-4,5-DIFLUOROPHENOX...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2More data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM86712(CAS_868359-05-1 | N-[4-(2-BROMO-4,5-DIFLUOROPHENOX...)copy SMILEScopy InChI
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibition of human EAAT3 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44ST4PubMed
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM86712(CAS_868359-05-1 | N-[4-(2-BROMO-4,5-DIFLUOROPHENOX...)copy SMILEScopy InChI
Affinity DataIC50: 851nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44ST4PubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM86712(CAS_868359-05-1 | N-[4-(2-BROMO-4,5-DIFLUOROPHENOX...)copy SMILEScopy InChI
Affinity DataIC50: 71nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 4(Rattus norvegicus)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM86712(CAS_868359-05-1 | N-[4-(2-BROMO-4,5-DIFLUOROPHENOX...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of rat EAAT4 expressed in tsA201 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44ST4PubMed
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM86712(CAS_868359-05-1 | N-[4-(2-BROMO-4,5-DIFLUOROPHENOX...)copy SMILEScopy InChI
Affinity DataIC50: 860nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44ST4PubMed
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM86712(CAS_868359-05-1 | N-[4-(2-BROMO-4,5-DIFLUOROPHENOX...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human EAAT3 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44ST4PubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM86712(CAS_868359-05-1 | N-[4-(2-BROMO-4,5-DIFLUOROPHENOX...)copy SMILEScopy InChI
Affinity DataIC50: 71nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM86712(CAS_868359-05-1 | N-[4-(2-BROMO-4,5-DIFLUOROPHENOX...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibitory concentration against glutamate uptake in oocytes expressing in human Excitatory amino acid transporter 2More data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM86712(CAS_868359-05-1 | N-[4-(2-BROMO-4,5-DIFLUOROPHENOX...)copy SMILEScopy InChI
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7FSPPubMed
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM86712(CAS_868359-05-1 | N-[4-(2-BROMO-4,5-DIFLUOROPHENOX...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7FSPPubMed
TargetExcitatory amino acid transporter 4(Rattus norvegicus)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM86712(CAS_868359-05-1 | N-[4-(2-BROMO-4,5-DIFLUOROPHENOX...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of rat EAAT4 expressed in tsA201 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44ST4PubMed