null

SMILES NC(=O)[C@H](CCC(O)=O)NC(=O)CCc1ccc(cc1)-c1cc(cs1)-c1ccccc1

InChI Key InChIKey=KDDWLGBIYXTPJG-FQEVSTJZSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 92445   

TargetMacrophage metalloelastase(Homo sapiens (Human))
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LigandPNGBDBM92445(Inhibitor, 10 | US8691753, 105)copy SMILEScopy InChI
Affinity DataKi:  3.60nM ΔG°:  -11.5kcal/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H993SBPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
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LigandPNGBDBM92445(Inhibitor, 10 | US8691753, 105)copy SMILEScopy InChI
Affinity DataKi:  3.65nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P5Z5QUS Patent
TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Homo sapiens (Human))
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LigandPNGBDBM92445(Inhibitor, 10 | US8691753, 105)copy SMILEScopy InChI
Affinity DataKi:  113nM ΔG°:  -9.47kcal/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H993SBPubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Commissariat A l'Energie Atomique et Aux Energies Alternatives

US Patent
LigandPNGBDBM92445(Inhibitor, 10 | US8691753, 105)copy SMILEScopy InChI
Affinity DataKi:  203nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P5Z5QUS Patent
TargetNeutrophil collagenase(Homo sapiens (Human))
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US Patent
LigandPNGBDBM92445(Inhibitor, 10 | US8691753, 105)copy SMILEScopy InChI
Affinity DataKi:  203nM ΔG°:  -9.12kcal/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H993SBPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
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LigandPNGBDBM92445(Inhibitor, 10 | US8691753, 105)copy SMILEScopy InChI
Affinity DataKi:  377nM ΔG°:  -8.76kcal/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H993SBPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Commissariat á l'Energie Atomique

LigandPNGBDBM92445(Inhibitor, 10 | US8691753, 105)copy SMILEScopy InChI
Affinity DataKi:  377nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P5Z5QUS Patent
TargetCollagenase 3(Homo sapiens (Human))
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LigandPNGBDBM92445(Inhibitor, 10 | US8691753, 105)copy SMILEScopy InChI
Affinity DataKi:  603nM ΔG°:  -8.48kcal/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H993SBPubMed
TargetCollagenase 3(Homo sapiens (Human))
Commissariat á l'Energie Atomique

LigandPNGBDBM92445(Inhibitor, 10 | US8691753, 105)copy SMILEScopy InChI
Affinity DataKi:  603nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P5Z5QUS Patent
TargetMatrix metalloproteinase-14 [1-20,P8S](Homo sapiens (Human))
Commissariat A l'Energie Atomique et Aux Energies Alternatives

US Patent
LigandPNGBDBM92445(Inhibitor, 10 | US8691753, 105)copy SMILEScopy InChI
Affinity DataKi: >1.00E+3nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P5Z5QUS Patent
TargetStromelysin-2(Homo sapiens (Human))
Commissariat A l'Energie Atomique et Aux Energies Alternatives

US Patent
LigandPNGBDBM92445(Inhibitor, 10 | US8691753, 105)copy SMILEScopy InChI
Affinity DataKi: >1.00E+3nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P5Z5QUS Patent
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Commissariat A l'Energie Atomique et Aux Energies Alternatives

US Patent
LigandPNGBDBM92445(Inhibitor, 10 | US8691753, 105)copy SMILEScopy InChI
Affinity DataKi: >1.00E+3nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P5Z5QUS Patent
TargetStromelysin-1(Homo sapiens (Human))
Commissariat A l'Energie Atomique et Aux Energies Alternatives

US Patent
LigandPNGBDBM92445(Inhibitor, 10 | US8691753, 105)copy SMILEScopy InChI
Affinity DataKi: >1.00E+3nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P5Z5QUS Patent
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Commissariat A l'Energie Atomique et Aux Energies Alternatives

US Patent
LigandPNGBDBM92445(Inhibitor, 10 | US8691753, 105)copy SMILEScopy InChI
Affinity DataKi:  2.63E+3nM ΔG°:  -7.61kcal/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H993SBPubMed
TargetStromelysin-1(Homo sapiens (Human))
Commissariat A l'Energie Atomique et Aux Energies Alternatives

US Patent
LigandPNGBDBM92445(Inhibitor, 10 | US8691753, 105)copy SMILEScopy InChI
Affinity DataKi:  3.00E+3nM ΔG°:  -7.53kcal/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H993SBPubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Commissariat á l'Energie Atomique

LigandPNGBDBM92445(Inhibitor, 10 | US8691753, 105)copy SMILEScopy InChI
Affinity DataKi:  3.01E+3nM ΔG°:  -7.53kcal/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H993SBPubMed
TargetStromelysin-2(Homo sapiens (Human))
Commissariat A l'Energie Atomique et Aux Energies Alternatives

US Patent
LigandPNGBDBM92445(Inhibitor, 10 | US8691753, 105)copy SMILEScopy InChI
Affinity DataKi:  3.11E+3nM ΔG°:  -7.51kcal/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H993SBPubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Commissariat á l'Energie Atomique

LigandPNGBDBM92445(Inhibitor, 10 | US8691753, 105)copy SMILEScopy InChI
Affinity DataKi:  4.20E+3nM ΔG°:  -7.62kcal/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H993SBPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Commissariat A l'Energie Atomique et Aux Energies Alternatives

US Patent
LigandPNGBDBM92445(Inhibitor, 10 | US8691753, 105)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P5Z5QUS Patent
TargetMatrilysin(Homo sapiens (Human))
Commissariat A l'Energie Atomique et Aux Energies Alternatives

US Patent
LigandPNGBDBM92445(Inhibitor, 10 | US8691753, 105)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P5Z5QUS Patent