Compile Data Set for Download or QSAR
Found 13 Enz. Inhib. hit(s) with Target = 'Hydroxyacylglutathione hydrolase, mitochondrial'
TargetHydroxyacylglutathione hydrolase, mitochondrial(Bos taurus)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50126960(CHEMBL3629116)copy SMILEScopy InChI
Affinity DataKi:  81nMAssay Description:Inhibition of bovine liver glyoxalase 2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4K7BPubMed
TargetHydroxyacylglutathione hydrolase, mitochondrial(Bos taurus)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50126961(CHEMBL3629115)copy SMILEScopy InChI
Affinity DataKi:  138nMAssay Description:Inhibition of bovine liver glyoxalase 2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4K7BPubMed
TargetHydroxyacylglutathione hydrolase, mitochondrial(Homo sapiens (Human))
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50039111(S-(N-Hydroxy-N-(4-bromophenyl)carbamoyl)glutathion...)copy SMILEScopy InChI
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition constants obtained from using the enediol analogs as competitive inhibitors for the inhibition of thehydrolysis of S-D-lactoylglutathione ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4RKKPubMed
TargetHydroxyacylglutathione hydrolase, mitochondrial(Bos taurus)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50092824(CHEMBL131578 | S-(N-4chlorophenyl-N-hydroxycarbamo...)copy SMILEScopy InChI
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of bovine liver glyoxalase 2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4K7BPubMed
TargetHydroxyacylglutathione hydrolase, mitochondrial(Homo sapiens (Human))
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50039108(S-(N-Hydroxy-N-(4-chlorophenyl)carbamoyl)glutathio...)copy SMILEScopy InChI
Affinity DataKi:  3.40E+3nMAssay Description:Inhibition constants obtained from using the enediol analogs as competitive inhibitors for the inhibition of thehydrolysis of S-D-lactoylglutathione ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4RKKPubMed
TargetHydroxyacylglutathione hydrolase, mitochondrial(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50026371(2-Amino-4-[1-(carboxymethyl-carbamoyl)-2-(4-nitro-...)copy SMILEScopy InChI
Affinity DataKi:  6.50E+3nMAssay Description:Binding affinity towards rat liver glyoxalase IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M32TRSPubMed
TargetHydroxyacylglutathione hydrolase, mitochondrial(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50026368(2-Amino-4-[1-(carboxymethyl-carbamoyl)-2-(3-nitro-...)copy SMILEScopy InChI
Affinity DataKi:  9.00E+3nMAssay Description:Binding affinity towards rat liver glyoxalase IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M32TRSPubMed
TargetHydroxyacylglutathione hydrolase, mitochondrial(Homo sapiens (Human))
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50039113(S-(N-Hydroxy-N-phenylcarbamoyl)glutathione)copy SMILEScopy InChI
Affinity DataKi:  1.10E+4nMAssay Description:Inhibition constant for the inhibition of the hydrolysis of S-D-lactoylglutathione by glyoxalase IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4RKKPubMed
TargetHydroxyacylglutathione hydrolase, mitochondrial(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50026370(2-Amino-4-[1-(carboxymethyl-carbamoyl)-2-(2-nitro-...)copy SMILEScopy InChI
Affinity DataKi:  1.50E+4nMAssay Description:Binding affinity towards rat liver glyoxalase IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M32TRSPubMed
TargetHydroxyacylglutathione hydrolase, mitochondrial(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50026369(2-Amino-4-[2-benzyloxycarbonylsulfanyl-1-(carboxym...)copy SMILEScopy InChI
Affinity DataKi:  6.50E+4nMAssay Description:Binding affinity towards rat liver glyoxalase IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M32TRSPubMed
TargetHydroxyacylglutathione hydrolase, mitochondrial(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50028202((S)-2-Amino-4-[(R)-2-benzyloxycarbonylsulfanyl-1-(...)copy SMILEScopy InChI
Affinity DataKi:  6.50E+4nMAssay Description:In vivo inhibitory activity of the compound against glyoxalase II in rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JNSPubMed
TargetHydroxyacylglutathione hydrolase, mitochondrial(Homo sapiens (Human))
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50039110(S-(N-Methyl-N-hydroxycarbomyl)ethylglutathione)copy SMILEScopy InChI
Affinity DataKi:  4.26E+5nMAssay Description:Inhibition constants obtained from using the enediol analogs as competitive inhibitors for the inhibition of thehydrolysis of S-D-lactoylglutathione ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4RKKPubMed
TargetHydroxyacylglutathione hydrolase, mitochondrial(Homo sapiens (Human))
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50582857(CHEMBL5091922)copy SMILES
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of recombinant human Glyoxalase-2 assessed as reduction of substrate level using S-D-lactoylglutathione as substrate by spectrophotometric...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56PM2PubMed