Compile Data Set for Download or QSAR
Found 233 Enz. Inhib. hit(s) with Target = 'Pyruvate kinase PKM'
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50455474(CHEMBL4218770)copy SMILEScopy InChI
Affinity DataKi:  50nMAssay Description:Irreversible binding affinity to recombinant human PKM2 expressed in Escherichia coli BL21More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82CWRPubMed
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM26664(7-Hydroxy-flavone, 5a | 7-Hydroxyflavone, 11 | 7-h...)copy SMILEScopy InChI
Affinity DataKi:  3.53E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M330SPPubMed
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50081950(6-Hydroxy-2-phenyl-chromen-4-one | 6-Hydroxyflavon...)copy SMILEScopy InChI
Affinity DataKi:  3.53E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M330SPPubMed
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50049385(5-Hydroxy-2-phenyl-chromen-4-one | 5-Hydroxyflavon...)copy SMILEScopy InChI
Affinity DataKi:  3.53E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M330SPPubMed
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50187668(3-Hydroxyflavone | 3-Hydroxyflavone (12) | 3-hydro...)copy SMILEScopy InChI
Affinity DataKi:  3.53E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M330SPPubMed
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50140257(5,7-Dihydroxy-8-methoxy-2-phenyl-chromen-4-one | 5...)copy SMILEScopy InChI
Affinity DataKi:  3.53E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M330SPPubMed
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50336799(5,5',5''-[1,3,6-naphthalenetriyltris(sulfonylimino...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+4nMAssay Description:Inhibitory activity against cell free dihydrofolate redutase (DHFR) from Escherichia coliMore data for this Ligand-Target Pair
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50336799(5,5',5''-[1,3,6-naphthalenetriyltris(sulfonylimino...)copy SMILEScopy InChI
Affinity DataKi:  1.65E+4nMAssay Description:Inhibitory activity against cell free dihydrofolate redutase (DHFR) from Escherichia coliMore data for this Ligand-Target Pair
TargetPyruvate kinase PKM(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50367051(CHEMBL606059)copy SMILEScopy InChI
Affinity DataKi:  5.00E+5nMAssay Description:Inhibition of rat muscle pyruvate kinase (PK-M)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21N81PWPubMed
TargetPyruvate kinase PKM(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50367051(CHEMBL606059)copy SMILEScopy InChI
Affinity DataKi:  5.00E+5nMAssay Description:Inhibition of rat muscle pyruvate kinase (PK-M)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21N81PWPubMed
TargetPyruvate kinase PKM(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50367052(CHEMBL605425)copy SMILEScopy InChI
Affinity DataKi:  9.00E+5nMAssay Description:Inhibition of rat muscle pyruvate kinase (PK-M)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21N81PWPubMed
TargetPyruvate kinase PKM(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50028624(CHEMBL3142978 | [6-(6-amino-9H-purin-9-yl)-2-methy...)copy SMILEScopy InChI
Affinity DataKi:  1.60E+6nMAssay Description:Inhibition of rat muscle pyruvate kinase (PK-M)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21N81PWPubMed
TargetPyruvate kinase PKM(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50367054(CHEMBL606476)copy SMILEScopy InChI
Affinity DataKi:  3.70E+6nMAssay Description:Inhibition of rat muscle pyruvate kinase (PK-M)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21N81PWPubMed
TargetPyruvate kinase PKM(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50367053(CHEMBL605428)copy SMILEScopy InChI
Affinity DataKi:  4.30E+6nMAssay Description:Inhibition of rat muscle pyruvate kinase (PK-M)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21N81PWPubMed
TargetPyruvate kinase PKM(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50367050(CHEMBL606006)copy SMILEScopy InChI
Affinity DataKi:  4.50E+6nMAssay Description:Inhibition of rat muscle pyruvate kinase (PK-M) at 10 mMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21N81PWPubMed
TargetPyruvate kinase PKM(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50367050(CHEMBL606006)copy SMILEScopy InChI
Affinity DataKi:  7.00E+6nMAssay Description:Inhibition of rat muscle pyruvate kinase (PK-M) at 6.7 mMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21N81PWPubMed
TargetPyruvate kinase PKM(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50028625(CHEMBL3142968 | [5-(6-amino-9H-purin-9-yl)-4-hydro...)copy SMILEScopy InChI
Affinity DataKi:  9.30E+6nMAssay Description:Inhibition of rat muscle pyruvate kinase (PK-M)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21N81PWPubMed
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM36609(Rapamycin C-7, analog 4 | SIROLIMUS | US11603377, ...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against cell free dihydrofolate redutase (DHFR) from Escherichia coliMore data for this Ligand-Target Pair
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50033731((R)-5,8-dihydroxy-2-(1-hydroxy-4-methylpent-3-enyl...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human N-terminal His6/SUMO-tagged PKM2 expressed in Escherichia coli BL21 using PEP as substrate incubated for 30 mins in p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40XS7PubMed
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50597717(CHEMBL3609603)copy SMILES
Affinity DataIC50: 650nMAssay Description:Inhibitory activity against cell free dihydrofolate redutase (DHFR) from Mycobacterium lufuMore data for this Ligand-Target Pair
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50597717(CHEMBL3609603)copy SMILES
Affinity DataIC50: 650nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M330SPPubMed
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50033731((R)-5,8-dihydroxy-2-(1-hydroxy-4-methylpent-3-enyl...)copy SMILEScopy InChI
Affinity DataIC50: 800nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M330SPPubMed
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50135169((-)-Catechin gallate | (2S,3R)-2-(3,4-dihydroxyphe...)copy SMILEScopy InChI
Affinity DataIC50: 850nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M330SPPubMed
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50135164(3,4,5-Trihydroxy-benzoic acid (2S,3S)-2-(3,4-dihyd...)copy SMILEScopy InChI
Affinity DataIC50: 850nMAssay Description:Inhibitory activity against cell free dihydrofolate reductase (DHFR) from Candida albicansMore data for this Ligand-Target Pair
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50597697(ALKANNIN | CHEBI:2578 | E103)copy SMILES
Affinity DataIC50: 900nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M330SPPubMed
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50597697(ALKANNIN | CHEBI:2578 | E103)copy SMILES
Affinity DataIC50: 900nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M330SPPubMed
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM7457(2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-4H-chromen-4...)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Inhibitory activity against cell free dihydrofolate redutase (DHFR) from Mycobacterium lufuMore data for this Ligand-Target Pair
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM7457(2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-4H-chromen-4...)copy SMILEScopy InChI
Affinity DataIC50: 900nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M330SPPubMed
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50597706(CHEMBL5189727)copy SMILES
Affinity DataIC50: 960nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M330SPPubMed
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM7458(5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one...)copy SMILEScopy InChI
Affinity DataIC50: 990nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M330SPPubMed
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM7458(5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one...)copy SMILEScopy InChI
Affinity DataIC50: 990nMAssay Description:Inhibitory activity against cell free dihydrofolate redutase (DHFR) from Escherichia coliMore data for this Ligand-Target Pair
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM7458(5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one...)copy SMILEScopy InChI
Affinity DataIC50: 990nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M330SPPubMed
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50084980((+)-taxifolin | (-)-Epicatechol | (2R,3R)-(-)-Epic...)copy SMILEScopy InChI
Affinity DataIC50: 1.16E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M330SPPubMed
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50084980((+)-taxifolin | (-)-Epicatechol | (2R,3R)-(-)-Epic...)copy SMILEScopy InChI
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibitory activity against cell free dihydrofolate reductase (DHFR) from Candida albicansMore data for this Ligand-Target Pair
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50081950(6-Hydroxy-2-phenyl-chromen-4-one | 6-Hydroxyflavon...)copy SMILEScopy InChI
Affinity DataIC50: 1.24E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M330SPPubMed
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50260539(CHEMBL80941)copy SMILEScopy InChI
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibitory activity against cell free dihydrofolate reductase (DHFR) from Candida albicansMore data for this Ligand-Target Pair
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM23417(α-CA inhibitor, 4 | (-)-Epicatechin | (2R,3R)...)copy SMILEScopy InChI
Affinity DataIC50: 1.33E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M330SPPubMed
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50049385(5-Hydroxy-2-phenyl-chromen-4-one | 5-Hydroxyflavon...)copy SMILEScopy InChI
Affinity DataIC50: 1.39E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M330SPPubMed
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50384788(LAPACHOL)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibitory activity against cell free dihydrofolate reductase (DHFR) from Candida albicansMore data for this Ligand-Target Pair
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50271046(CHEMBL4127005)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM2 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B62NMPubMed
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50009353(1,5,10-triazadecane | 4-azaoctamethylenediamine | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.41E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M330SPPubMed
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50033731((R)-5,8-dihydroxy-2-(1-hydroxy-4-methylpent-3-enyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibitory activity against cell free dihydrofolate reductase (DHFR) from Candida albicansMore data for this Ligand-Target Pair
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50271056(CHEMBL4127111)copy SMILEScopy InChI
Affinity DataIC50: 1.74E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM2 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B62NMPubMed
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50187668(3-Hydroxyflavone | 3-Hydroxyflavone (12) | 3-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 1.75E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M330SPPubMed
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50597715(CHEMBL4877010)copy SMILES
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity against cell free dihydrofolate redutase (DHFR) from Mycobacterium lufuMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50597715(CHEMBL4877010)copy SMILES
Affinity DataIC50: 2.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M330SPPubMed
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50140257(5,7-Dihydroxy-8-methoxy-2-phenyl-chromen-4-one | 5...)copy SMILEScopy InChI
Affinity DataIC50: 2.01E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M330SPPubMed
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM26664(7-Hydroxy-flavone, 5a | 7-Hydroxyflavone, 11 | 7-h...)copy SMILEScopy InChI
Affinity DataIC50: 2.12E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M330SPPubMed
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50271044(CHEMBL4125726)copy SMILEScopy InChI
Affinity DataIC50: 2.21E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM2 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B62NMPubMed
TargetPyruvate kinase PKM(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50271058(CHEMBL4128346)copy SMILEScopy InChI
Affinity DataIC50: 2.58E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM2 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B62NMPubMed
Displayed 1 to 50 (of 233 total ) | Next | Last >>
Jump to: