Compile Data Set for Download or QSAR
Found 58 Enz. Inhib. hit(s) with Target = 'Sphingolipid delta(4)-desaturase DES1'
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM50407243(CHEMBL5275998)copy SMILEScopy InChI
Affinity DataKi:  22nMAssay Description:Negative log concentration of antagonist was determined on 5-hydroxytryptamine 2B receptor of Rat stomach fundusMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM50312869(4-(4-(4-chlorophenyl)thiazol-2-ylamino)phenol | CH...)copy SMILEScopy InChI
Affinity DataKi:  300nMAssay Description:Negative log concentration of antagonist on 5-hydroxytryptamine 2A receptor in rat thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingolipid delta(4)-desaturase DES1(Rattus norvegicus)TBA
LigandPNGBDBM50092055((2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cycl...)copy SMILEScopy InChI
Affinity DataKi:  8.28E+3nMAssay Description:Negative log concentration of antagonist on 5-hydroxytryptamine 2A receptor in rat thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523251(N-(5-hydroxy- pyridin-2-yl)-7- methyloctan- amide ...)copy SMILES
Affinity DataIC50: 1nMAssay Description:Negative log concentration of antagonist on 5-hydroxytryptamine 2A receptor in rat thoracic aortaMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523251(N-(5-hydroxy- pyridin-2-yl)-7- methyloctan- amide ...)copy SMILES
Affinity DataIC50: 1nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92FGHUS Patent
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523252((1r,4r)-4-(4- chlorophenyl)- N-(5-hydroxy- pyridin...)copy SMILES
Affinity DataIC50: 1nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92FGHUS Patent
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523252((1r,4r)-4-(4- chlorophenyl)- N-(5-hydroxy- pyridin...)copy SMILES
Affinity DataIC50: 1nMAssay Description:Negative log concentration of antagonist was determined on 5-hydroxytryptamine 2B receptor of Rat stomach fundusMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523268(N-(5-hydroxypyridin-2-yl)-1-[4-(trifluoromethyl)ph...)copy SMILES
Affinity DataIC50: 2nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92FGHUS Patent
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523246(N-(5-hydroxy- pyridin-2-yl)- 4'-chloro- biphenyl-4...)copy SMILES
Affinity DataIC50: 3nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92FGHUS Patent
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523270(2-[1-(5-chloropyridin-2-yl)piperidin-4-yl]-N-(5-hy...)copy SMILES
Affinity DataIC50: 3.90nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92FGHUS Patent
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523254(4-(tert-butyl)- N-(5-hydroxy- pyridin-2-yl)- benza...)copy SMILES
Affinity DataIC50: 4nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92FGHUS Patent
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523243(N-(5-hydroxy- pyridin-2-yl)- 4-cyclohexyl- benzami...)copy SMILES
Affinity DataIC50: 4nMAssay Description:Negative log concentration of antagonist was determined on 5-hydroxytryptamine 2B receptor of Rat stomach fundusMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523243(N-(5-hydroxy- pyridin-2-yl)- 4-cyclohexyl- benzami...)copy SMILES
Affinity DataIC50: 4nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92FGHUS Patent
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523266(2-[1-(4-chlorophenyl)piperidin-4-yl]-N-(5-hydroxyp...)copy SMILES
Affinity DataIC50: 5nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92FGHUS Patent
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523249((1r,4r)-N-(5- hydroxy- pyridin-2-yl)- 4-phenyl- cy...)copy SMILES
Affinity DataIC50: 5nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92FGHUS Patent
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523245(N-(5-hydroxy- pyridin-2-yl)- 4'-cyano- biphenyl-4-...)copy SMILES
Affinity DataIC50: 5nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92FGHUS Patent
TargetSphingolipid delta(4)-desaturase DES1(Rattus norvegicus)TBA
LigandPNGBDBM50407243(CHEMBL5275998)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Negative log concentration of antagonist was determined on 5-hydroxytryptamine 2B receptor of Rat stomach fundusMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523250(N-(5-hydroxy- pyridin-2-yl)- octanamide | US111352...)copy SMILES
Affinity DataIC50: 6nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92FGHUS Patent
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523236(N-(5-hydroxy- pyridin-2-yl)- (1,1'- biphenyl)-4- c...)copy SMILES
Affinity DataIC50: 10nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92FGHUS Patent
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523269(1-(4-fluorophenyl)-N-(5-hydroxypyridin-2-yl)piperi...)copy SMILES
Affinity DataIC50: 11nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92FGHUS Patent
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523264(2-[1-(4-fluorophenyl) piperidin-4-yl]-N-(5-hydroxy...)copy SMILES
Affinity DataIC50: 13nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92FGHUS Patent
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523244(N-(5-hydroxy- pyridin-2-yl)- 4'-methoxy- biphenyl-...)copy SMILES
Affinity DataIC50: 14nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92FGHUS Patent
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523248(N-(5-hydroxy- pyridin-2-yl)- 4-isopropyl- benzamid...)copy SMILES
Affinity DataIC50: 16nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92FGHUS Patent
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523256(2'-chloro-N- (5-hydroxy- pyridin-2-yl)- [1,1'- bip...)copy SMILES
Affinity DataIC50: 19nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92FGHUS Patent
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523255(N-(5-hydroxy- pyridin-2-yl)- 5-isopropoxy- pentana...)copy SMILES
Affinity DataIC50: 21nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92FGHUS Patent
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523257((1r,4r)-N-(5- hydroxypyridin- 2-yl)-4-iso- propoxy...)copy SMILES
Affinity DataIC50: 21nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92FGHUS Patent
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523261(N-(5-hydroxy- pyridin-2-yl)- 4-(1,1,1- trifluoro- ...)copy SMILES
Affinity DataIC50: 23nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92FGHUS Patent
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523232(N-(4-hydroxy- phcnyl)-[1,1'- biphenyl]-4- carboxam...)copy SMILES
Affinity DataIC50: 50nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92FGHUS Patent
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523262(N-(5-hydroxypyridin-2-yl)-2-[4-[4-(trifluoromethyl...)copy SMILES
Affinity DataIC50: 50nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92FGHUS Patent
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM50407243(CHEMBL5275998)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Negative log concentration of antagonist on 5-hydroxytryptamine 2A receptor in rat thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523235(N-(5-hydroxy- pyridin-2-yl)- cinnamide | US1113520...)copy SMILES
Affinity DataIC50: 60nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92FGHUS Patent
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523260(N-(5-hydroxy- pyridin-2-yl)- 4-(trifluoro- methyl)...)copy SMILES
Affinity DataIC50: 63nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92FGHUS Patent
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523267(2-[4-(4-chlorophenyl)piperazin-1-yl]-N-(5-hydroxyp...)copy SMILES
Affinity DataIC50: 66nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92FGHUS Patent
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523258((1s,4s)-N-(5- hydroxypyridin- 2-yl)-4-iso- propoxy...)copy SMILES
Affinity DataIC50: 88nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92FGHUS Patent
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523241(N-(4-hydroxy- phenyl)-4- cyclohexyl- benzamide | U...)copy SMILES
Affinity DataIC50: 90nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92FGHUS Patent
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523241(N-(4-hydroxy- phenyl)-4- cyclohexyl- benzamide | U...)copy SMILES
Affinity DataIC50: 90nMAssay Description:Negative log concentration of antagonist on 5-hydroxytryptamine 2A receptor in rat thoracic aortaMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM50092055((2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cycl...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Negative log concentration of antagonist was determined on 5-hydroxytryptamine 2B receptor of Rat stomach fundusMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523253(N-(5-hydroxy- pyridin-2-yl)- 4-(pyridin-3- yl)benz...)copy SMILES
Affinity DataIC50: 130nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92FGHUS Patent
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523259(4-ethyl-N-(5- hydroxy- pyridin-2-yl)- benzamide | ...)copy SMILES
Affinity DataIC50: 130nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92FGHUS Patent
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523265(2-[4-(4-fluorophenyl)piperazin-1-yl]-N-(5-hydroxyp...)copy SMILES
Affinity DataIC50: 140nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92FGHUS Patent
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM50407244(CHEMBL5268107)copy SMILEScopy InChI
Affinity DataIC50: 155nMAssay Description:Negative log concentration of antagonist on 5-hydroxytryptamine 2A receptor in rat thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523234(N-(5-hydroxy- pyridin-2-yl)- 2-naphth- amide | US1...)copy SMILES
Affinity DataIC50: 180nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92FGHUS Patent
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523237((trans)-N-(5- hydroxy- pyridin-2-yl)- 2-phenyl- cy...)copy SMILES
Affinity DataIC50: 230nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92FGHUS Patent
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523247(N-(5-hydroxy- pyridin-2-yl)- 4-methoxy- benzamide ...)copy SMILES
Affinity DataIC50: 240nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92FGHUS Patent
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523263(1-(4-fluorophenyl)-N-(5-hydroxypyridin-2-yl)piperi...)copy SMILES
Affinity DataIC50: 250nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92FGHUS Patent
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM50429763(CHEMBL229844 | N-(4-Hydroxyphenyl)Cinnamamide | US...)copy SMILEScopy InChI
Affinity DataIC50: 440nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92FGHUS Patent
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523233((trans)-N-(4- hydroxyphenyl)- 2-phenyl- cyclopropa...)copy SMILES
Affinity DataIC50: 590nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92FGHUS Patent
TargetSphingolipid delta(4)-desaturase DES1(Homo sapiens (Human))TBA
LigandPNGBDBM523229(N-(4-hydroxy- phenyl)-2- naphthamide | US11135207,...)copy SMILES
Affinity DataIC50: 840nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92FGHUS Patent
TargetSphingolipid delta(4)-desaturase DES1(Rattus norvegicus)TBA
LigandPNGBDBM50407241(CHEMBL5290345)copy SMILEScopy InChI
Affinity DataIC50: 1.68E+3nMAssay Description:Negative log concentration of antagonist on 5-hydroxytryptamine 2A receptor in rat thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingolipid delta(4)-desaturase DES1(Rattus norvegicus)TBA
LigandPNGBDBM50092055((2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cycl...)copy SMILEScopy InChI
Affinity DataIC50: 2.32E+3nMAssay Description:Negative log concentration of antagonist was determined on 5-hydroxytryptamine 2B receptor of Rat stomach fundusMore data for this Ligand-Target Pair
In DepthDetails
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