Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£ degli Studi di Pisa
Curated by ChEMBL
Universit£ degli Studi di Pisa
Curated by ChEMBL
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of human matrix metalloprotease-2More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£ degli Studi di Pisa
Curated by ChEMBL
Universit£ degli Studi di Pisa
Curated by ChEMBL
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of human matrix metalloprotease-2More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£ degli Studi di Pisa
Curated by ChEMBL
Universit£ degli Studi di Pisa
Curated by ChEMBL
Affinity DataIC50: 0.130nMAssay Description:Inhibition of recombinant human activated-MMP2 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as fluorogenic substrate incubated for 4 hrs follow...More data for this Ligand-Target Pair
Affinity DataIC50: 0.190nMAssay Description:Inhibition of recombinant human activated-MMP13 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as fluorogenic substrate incubated for 4 hrs follo...More data for this Ligand-Target Pair
Affinity DataIC50: 0.230nMAssay Description:Inhibition of human matrix metalloprotease-3More data for this Ligand-Target Pair
Affinity DataIC50: 0.25nMAssay Description:Inhibition of recombinant human activated-MMP13 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as fluorogenic substrate incubated for 4 hrs follo...More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£ degli Studi di Pisa
Curated by ChEMBL
Universit£ degli Studi di Pisa
Curated by ChEMBL
Affinity DataIC50: 0.260nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Universit£ degli Studi di Pisa
Curated by ChEMBL
Universit£ degli Studi di Pisa
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human matrix metalloprotease-14More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£ degli Studi di Pisa
Curated by ChEMBL
Universit£ degli Studi di Pisa
Curated by ChEMBL
Affinity DataIC50: 0.330nMAssay Description:Inhibition of recombinant human activated-MMP2 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as fluorogenic substrate incubated for 4 hrs follow...More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£ degli Studi di Pisa
Curated by ChEMBL
Universit£ degli Studi di Pisa
Curated by ChEMBL
Affinity DataIC50: 0.370nMAssay Description:Inhibition of recombinant human activated-MMP2 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as fluorogenic substrate incubated for 4 hrs follow...More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£ degli Studi di Pisa
Curated by ChEMBL
Universit£ degli Studi di Pisa
Curated by ChEMBL
Affinity DataIC50: 0.410nMAssay Description:Inhibition of human matrix metalloprotease-2More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£ degli Studi di Pisa
Curated by ChEMBL
Universit£ degli Studi di Pisa
Curated by ChEMBL
Affinity DataIC50: 0.430nMAssay Description:Inhibition of recombinant human activated-MMP9 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as fluorogenic substrate incubated for 4 hrs follow...More data for this Ligand-Target Pair
Affinity DataIC50: 0.580nMAssay Description:Inhibition of recombinant human activated-MMP13 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as fluorogenic substrate incubated for 4 hrs follo...More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£ degli Studi di Pisa
Curated by ChEMBL
Universit£ degli Studi di Pisa
Curated by ChEMBL
Affinity DataIC50: 0.670nMAssay Description:Inhibition of recombinant human activated-MMP2 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as fluorogenic substrate incubated for 4 hrs follow...More data for this Ligand-Target Pair
Affinity DataIC50: 0.680nMAssay Description:Inhibition of recombinant human activated-MMP13 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as fluorogenic substrate incubated for 4 hrs follo...More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£ degli Studi di Pisa
Curated by ChEMBL
Universit£ degli Studi di Pisa
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human activated-MMP2 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as fluorogenic substrate incubated for 4 hrs follow...More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£ degli Studi di Pisa
Curated by ChEMBL
Universit£ degli Studi di Pisa
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant human activated-MMP2 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as fluorogenic substrate incubated for 4 hrs follow...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant human activated-MMP13 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as fluorogenic substrate incubated for 4 hrs follo...More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£ degli Studi di Pisa
Curated by ChEMBL
Universit£ degli Studi di Pisa
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant human activated-MMP2 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as fluorogenic substrate incubated for 4 hrs follow...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human matrix metalloprotease-8More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£ degli Studi di Pisa
Curated by ChEMBL
Universit£ degli Studi di Pisa
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human matrix metalloprotease-2More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£ degli Studi di Pisa
Curated by ChEMBL
Universit£ degli Studi di Pisa
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human activated-MMP9 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as fluorogenic substrate incubated for 4 hrs follow...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of recombinant human activated-MMP13 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as fluorogenic substrate incubated for 4 hrs follo...More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£ degli Studi di Pisa
Curated by ChEMBL
Universit£ degli Studi di Pisa
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition of recombinant human activated-MMP9 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as fluorogenic substrate incubated for 4 hrs follow...More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Universit£ degli Studi di Pisa
Curated by ChEMBL
Universit£ degli Studi di Pisa
Curated by ChEMBL
Affinity DataIC50: 3.90nMAssay Description:Inhibition of recombinant human catalytic domain MMP14 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as fluorogenic substrate incubated for 4 hr...More data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:Inhibition of recombinant human activated-MMP13 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as fluorogenic substrate incubated for 4 hrs follo...More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£ degli Studi di Pisa
Curated by ChEMBL
Universit£ degli Studi di Pisa
Curated by ChEMBL
Affinity DataIC50: 6.40nMAssay Description:Inhibition of recombinant human activated-MMP9 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as fluorogenic substrate incubated for 4 hrs follow...More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£ degli Studi di Pisa
Curated by ChEMBL
Universit£ degli Studi di Pisa
Curated by ChEMBL
Affinity DataIC50: 6.5nMAssay Description:Inhibition of recombinant human activated-MMP9 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as fluorogenic substrate incubated for 4 hrs follow...More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£ degli Studi di Pisa
Curated by ChEMBL
Universit£ degli Studi di Pisa
Curated by ChEMBL
Affinity DataIC50: 6.70nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Universit£ degli Studi di Pisa
Curated by ChEMBL
Universit£ degli Studi di Pisa
Curated by ChEMBL
Affinity DataIC50: 7.70nMAssay Description:Inhibition of human matrix metalloprotease-14More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£ degli Studi di Pisa
Curated by ChEMBL
Universit£ degli Studi di Pisa
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
Affinity DataIC50: 8.20nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£ degli Studi di Pisa
Curated by ChEMBL
Universit£ degli Studi di Pisa
Curated by ChEMBL
Affinity DataIC50: 8.60nMAssay Description:Inhibition of recombinant human activated-MMP9 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as fluorogenic substrate incubated for 4 hrs follow...More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Universit£ degli Studi di Pisa
Curated by ChEMBL
Universit£ degli Studi di Pisa
Curated by ChEMBL
Affinity DataIC50: 8.90nMAssay Description:Inhibition of human matrix metalloprotease-14More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£ degli Studi di Pisa
Curated by ChEMBL
Universit£ degli Studi di Pisa
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant human activated-MMP9 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as fluorogenic substrate incubated for 4 hrs follow...More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Universit£ degli Studi di Pisa
Curated by ChEMBL
Universit£ degli Studi di Pisa
Curated by ChEMBL
Affinity DataIC50: 9.80nMAssay Description:Inhibition of human matrix metalloprotease-14More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£ degli Studi di Pisa
Curated by ChEMBL
Universit£ degli Studi di Pisa
Curated by ChEMBL
Affinity DataIC50: 10.3nMAssay Description:Inhibition of human matrix metalloprotease-2More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£ degli Studi di Pisa
Curated by ChEMBL
Universit£ degli Studi di Pisa
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of human matrix metalloprotease-2More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£ degli Studi di Pisa
Curated by ChEMBL
Universit£ degli Studi di Pisa
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£ degli Studi di Pisa
Curated by ChEMBL
Universit£ degli Studi di Pisa
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£ degli Studi di Pisa
Curated by ChEMBL
Universit£ degli Studi di Pisa
Curated by ChEMBL
Affinity DataIC50: 19.6nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human activated-MMP3 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as fluorogenic substrate incubated for 4 hrs follow...More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of human matrix metalloprotease-3More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Universit£ degli Studi di Pisa
Curated by ChEMBL
Universit£ degli Studi di Pisa
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human catalytic domain MMP14 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as fluorogenic substrate incubated for 4 hr...More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Universit£ degli Studi di Pisa
Curated by ChEMBL
Universit£ degli Studi di Pisa
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human catalytic domain MMP14 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as fluorogenic substrate incubated for 4 hr...More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant human activated-MMP3 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as fluorogenic substrate incubated for 4 hrs follow...More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Universit£ degli Studi di Pisa
Curated by ChEMBL
Universit£ degli Studi di Pisa
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Inhibition of recombinant human catalytic domain MMP14 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as fluorogenic substrate incubated for 4 hr...More data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of recombinant human activated-MMP3 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as fluorogenic substrate incubated for 4 hrs follow...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of human matrix metalloprotease-3More data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibition of human matrix metalloprotease-7More data for this Ligand-Target Pair