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Found 702 with Last Name = 'edwards' and Initial = 'a'
TargetE3 ubiquitin-protein ligase SMURF1(Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM239101(US10195181, Example 2.2 | US9403810, 2.2)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:To determine the HECT E3 ligase selectivity of the compounds, a panel of biochemical HECT E3 ligase autoubiquitinylation assays was employed (Smurf-1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28054Q2US Patent
TargetE3 ubiquitin-protein ligase SMURF1 [420-757](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM239101(US10195181, Example 2.2 | US9403810, 2.2)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMT: 2°CAssay Description:For the biochemical assay panel, 50 nl of the test compounds, reference compounds and buffer/DMSO control are transferred to the respective wells of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22V2F1FUS Patent
TargetE3 ubiquitin-protein ligase SMURF1 [420-757](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM239132(US9403810, 22c)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMT: 2°CAssay Description:For the biochemical assay panel, 50 nl of the test compounds, reference compounds and buffer/DMSO control are transferred to the respective wells of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22V2F1FUS Patent
TargetE3 ubiquitin-protein ligase SMURF1(Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM239117(US10195181, Example 22c | US9403810, 22)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:To determine the HECT E3 ligase selectivity of the compounds, a panel of biochemical HECT E3 ligase autoubiquitinylation assays was employed (Smurf-1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28054Q2US Patent
TargetE3 ubiquitin-protein ligase SMURF1(Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM239094(US10195181, Example 1.3 | US9403810, 1.3)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:To determine the HECT E3 ligase selectivity of the compounds, a panel of biochemical HECT E3 ligase autoubiquitinylation assays was employed (Smurf-1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28054Q2US Patent
TargetE3 ubiquitin-protein ligase SMURF1 [420-757](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM239094(US10195181, Example 1.3 | US9403810, 1.3)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMT: 2°CAssay Description:For the biochemical assay panel, 50 nl of the test compounds, reference compounds and buffer/DMSO control are transferred to the respective wells of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22V2F1FUS Patent
TargetActivin receptor type-1(Homo sapiens (Human))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50528195(CHEMBL4435320)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of ALK2 G328V mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6HB1PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50528203(CHEMBL4434694)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of ALK2 G328V mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6HB1PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50528195(CHEMBL4435320)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of ALK2 R258G mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6HB1PubMed
TargetE3 ubiquitin-protein ligase SMURF1 [420-757](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM239092(US10195181, Example 1.1 | US9403810, 1.1)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMT: 2°CAssay Description:For the biochemical assay panel, 50 nl of the test compounds, reference compounds and buffer/DMSO control are transferred to the respective wells of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22V2F1FUS Patent
TargetE3 ubiquitin-protein ligase SMURF1(Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM239092(US10195181, Example 1.1 | US9403810, 1.1)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:To determine the HECT E3 ligase selectivity of the compounds, a panel of biochemical HECT E3 ligase autoubiquitinylation assays was employed (Smurf-1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28054Q2US Patent
TargetPantothenate kinase 3(Homo sapiens (Human))TBA
LigandPNGBDBM649476(US11891378, Example 6)copy SMILES
Affinity DataIC50: 2.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetE3 ubiquitin-protein ligase SMURF1 [420-757](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM239099(US10195181, Example 2 | US9403810, 2)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMT: 2°CAssay Description:For the biochemical assay panel, 50 nl of the test compounds, reference compounds and buffer/DMSO control are transferred to the respective wells of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22V2F1FUS Patent
TargetE3 ubiquitin-protein ligase SMURF1(Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM239099(US10195181, Example 2 | US9403810, 2)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:To determine the HECT E3 ligase selectivity of the compounds, a panel of biochemical HECT E3 ligase autoubiquitinylation assays was employed (Smurf-1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28054Q2US Patent
TargetE3 ubiquitin-protein ligase SMURF1(Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM239091(US10195181, Example 1 | US9403810, 1)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:To determine the HECT E3 ligase selectivity of the compounds, a panel of biochemical HECT E3 ligase autoubiquitinylation assays was employed (Smurf-1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28054Q2US Patent
TargetE3 ubiquitin-protein ligase SMURF1 [420-757](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM239091(US10195181, Example 1 | US9403810, 1)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMT: 2°CAssay Description:For the biochemical assay panel, 50 nl of the test compounds, reference compounds and buffer/DMSO control are transferred to the respective wells of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22V2F1FUS Patent
TargetPantothenate kinase 3(Homo sapiens (Human))TBA
LigandPNGBDBM649472(US11891378, Example 2)copy SMILES
Affinity DataIC50: 2.90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetActivin receptor type-1(Homo sapiens (Human))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50528195(CHEMBL4435320)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of 10 uM [gamma33P] ATP by radioactive assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6HB1PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50544399(CHEMBL4638273)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GV3PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50528196(CHEMBL4575655)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of 10 uM [gamma33P] ATP by radioactive assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6HB1PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50528190(CHEMBL4548795)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of ALK2 G328V mutant (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6HB1PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50528209(CHEMBL4526828)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of 10 uM [gamma33P] ATP by radioactive assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6HB1PubMed
TargetE3 ubiquitin-protein ligase SMURF1(Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM239095(US10195181, Example 1.4 | US9403810, 1.4)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:To determine the HECT E3 ligase selectivity of the compounds, a panel of biochemical HECT E3 ligase autoubiquitinylation assays was employed (Smurf-1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28054Q2US Patent
TargetE3 ubiquitin-protein ligase SMURF1 [420-757](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM239095(US10195181, Example 1.4 | US9403810, 1.4)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMT: 2°CAssay Description:For the biochemical assay panel, 50 nl of the test compounds, reference compounds and buffer/DMSO control are transferred to the respective wells of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22V2F1FUS Patent
LigandPNGBDBM525146(US11168102, Example 32-31.)copy SMILES
Affinity DataIC50: 3.53nMAssay Description:Using a GE Biacore 8K SPR instrument, avi-tagged SOS1 catalytic domain protein was immobilized to a level of approximately 6000 response units (RU) o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5J3DUS Patent
TargetPantothenate kinase 3(Homo sapiens (Human))TBA
LigandPNGBDBM649480(US11891378, Example 10)copy SMILES
Affinity DataIC50: 3.80nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetActivin receptor type-1(Homo sapiens (Human))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50528195(CHEMBL4435320)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human ALK2 R206H mutant using casein as substrate in presence of 10 uM [gamma33P] ATP by radioactive assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6HB1PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50528203(CHEMBL4434694)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of ALK2 R258G mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6HB1PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50528208(CHEMBL4440168)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of ALK2 G328V mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6HB1PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50544408(CHEMBL4641207)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GV3PubMed
LigandPNGBDBM525147(US11168102, Example 32-32.)copy SMILES
Affinity DataIC50: 4.77nMAssay Description:Using a GE Biacore 8K SPR instrument, avi-tagged SOS1 catalytic domain protein was immobilized to a level of approximately 6000 response units (RU) o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5J3DUS Patent
TargetActivin receptor type-1(Homo sapiens (Human))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50528203(CHEMBL4434694)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human ALK2 R206H mutant using casein as substrate in presence of 10 uM [gamma33P] ATP by radioactive assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6HB1PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50544414(CHEMBL4641530)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GV3PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50528204(CHEMBL4565968)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of 10 uM [gamma33P] ATP by radioactive assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6HB1PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50528190(CHEMBL4548795)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of 10 uM [gamma33P] ATP by radioactive assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6HB1PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50528188(CHEMBL4553210)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of ALK2 G328V mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetActivin receptor type-1(Homo sapiens (Human))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50528205(CHEMBL4468389)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of 10 uM [gamma33P] ATP by radioactive assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6HB1PubMed
TargetPantothenate kinase 3(Homo sapiens (Human))TBA
LigandPNGBDBM649479(US11891378, Example 9)copy SMILES
Affinity DataIC50: 5.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetE3 ubiquitin-protein ligase SMURF1 [420-757](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM239105(US10195181, Example 6 | US9403810, 6)copy SMILEScopy InChI
Affinity DataIC50: 5.70nMT: 2°CAssay Description:For the biochemical assay panel, 50 nl of the test compounds, reference compounds and buffer/DMSO control are transferred to the respective wells of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22V2F1FUS Patent
TargetE3 ubiquitin-protein ligase SMURF1(Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM239105(US10195181, Example 6 | US9403810, 6)copy SMILEScopy InChI
Affinity DataIC50: 5.70nMAssay Description:To determine the HECT E3 ligase selectivity of the compounds, a panel of biochemical HECT E3 ligase autoubiquitinylation assays was employed (Smurf-1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28054Q2US Patent
LigandPNGBDBM525070(US11168102, Example 18.)copy SMILES
Affinity DataIC50: 5.79nMAssay Description:Using a GE Biacore 8K SPR instrument, avi-tagged SOS1 catalytic domain protein was immobilized to a level of approximately 6000 response units (RU) o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5J3DUS Patent
TargetPantothenate kinase 3(Homo sapiens (Human))TBA
LigandPNGBDBM649477(US11891378, Example 7)copy SMILES
Affinity DataIC50: 5.80nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetActivin receptor type-1(Homo sapiens (Human))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50544419(CHEMBL4647724)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GV3PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50528190(CHEMBL4548795)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human ALK2 R206H mutant using casein as substrate in presence of 10 uM [gamma33P] ATP by radioactive assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6HB1PubMed
TargetE3 ubiquitin-protein ligase SMURF1(Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM239102(US10195181, Example 3 | US9403810, 3)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:To determine the HECT E3 ligase selectivity of the compounds, a panel of biochemical HECT E3 ligase autoubiquitinylation assays was employed (Smurf-1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28054Q2US Patent
TargetActivin receptor type-1(Homo sapiens (Human))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50528194(CHEMBL4517408)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Competitive displacement of PBI-6908 from nanoluciferase-fused ALK2 G328V mutant (unknown origin) expressed in HEK293 cells incubated for 2 hrs by Na...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetActivin receptor type-1(Homo sapiens (Human))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50544418(CHEMBL4648102)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GV3PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50528190(CHEMBL4548795)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of ALK2 R258G mutant (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6HB1PubMed
TargetE3 ubiquitin-protein ligase SMURF1 [420-757](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM239096(US10195181, Example 1.5 | US9403810, 1.5)copy SMILEScopy InChI
Affinity DataIC50: 6nMT: 2°CAssay Description:For the biochemical assay panel, 50 nl of the test compounds, reference compounds and buffer/DMSO control are transferred to the respective wells of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22V2F1FUS Patent
TargetE3 ubiquitin-protein ligase SMURF1 [420-757](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM239102(US10195181, Example 3 | US9403810, 3)copy SMILEScopy InChI
Affinity DataIC50: 6nMT: 2°CAssay Description:For the biochemical assay panel, 50 nl of the test compounds, reference compounds and buffer/DMSO control are transferred to the respective wells of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22V2F1FUS Patent
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