Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase SMURF1' and Ligand = 'BDBM239101'
TargetE3 ubiquitin-protein ligase SMURF1(Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM239101(US10195181, Example 2.2 | US9403810, 2.2)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:To determine the HECT E3 ligase selectivity of the compounds, a panel of biochemical HECT E3 ligase autoubiquitinylation assays was employed (Smurf-1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28054Q2US Patent
TargetE3 ubiquitin-protein ligase SMURF1(Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM239101(US10195181, Example 2.2 | US9403810, 2.2)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of N-terminal Prolabel-tagged human Smurf-1 HECT domain expressed in HEK293 cells assessed as accumulation of Smurf-1 protein using chemil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S2BPubMed