Compile Data Set for Download or QSAR
Found 160 with Last Name = 'romero' and Initial = 'af'
TargetHistone acetyltransferase KAT2B [719-832](Homo sapiens (Human))
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM311486(CHEM-US-00192 | US10155764, Example 65B)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M67T9US Patent
TargetHistone acetyltransferase KAT2B [719-832](Homo sapiens (Human))
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM311498(CHEM-US-00210 | US10155764, Example 74A)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M67T9US Patent
TargetBromodomain-containing protein 9 [134-239](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310899(4-[4-(1-hydroxy-1-methyl-ethyl)phenyl]-6-methyl-1H...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetHistone acetyltransferase KAT2B [719-832](Homo sapiens (Human))
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM311480(CHEM-US-00186 | US10155764, Example 60)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M67T9US Patent
TargetHistone acetyltransferase KAT2B [719-832](Homo sapiens (Human))
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM311495(CHEM-US-00207 | US10155764, Example 73A)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M67T9US Patent
TargetBromodomain-containing protein 9 [134-239](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310892(N-(2-methoxyethyl)-4-(6-methyl-7-oxo-1H-pyrrolo[2,...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetHistone acetyltransferase KAT2B [719-832](Homo sapiens (Human))
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM311483(CHEM-US-00189 | US10155764, Example 63)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M67T9US Patent
TargetBromodomain-containing protein 9 [134-239](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310896(7-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetHistone acetyltransferase KAT2B [719-832](Homo sapiens (Human))
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM311512(CHEM-US-00232 | US10155764, Example 87)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M67T9US Patent
TargetHistone acetyltransferase KAT2B [719-832](Homo sapiens (Human))
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM311511(US10155764, Example 86)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M67T9US Patent
TargetBromodomain-containing protein 9 [134-239](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310895(3-methyl-7-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridi...)copy SMILES
Affinity DataIC50: 31nMAssay Description:His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetHistone acetyltransferase KAT2B [719-832](Homo sapiens (Human))
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM311479(CHEM-US-00185 | US10155764, Example 59)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M67T9US Patent
TargetChromatin remodeling regulator CECR2 [424-538](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310905(2-methyl-7-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridi...)copy SMILES
Affinity DataIC50: 36nMAssay Description:His/Flag epitope tagged CECR2424-538 was cloned, expressed, and purified to homogeneity. CECR2 binding and inhibition was assessed by monitoring the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetHistone acetyltransferase KAT2B [719-832](Homo sapiens (Human))
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM311502(US10155764, Example 77)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M67T9US Patent
TargetHistone acetyltransferase KAT2B [719-832](Homo sapiens (Human))
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM311490(CHEM-US-00202 | US10155764, Example 70A)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M67T9US Patent
TargetHistone acetyltransferase KAT2B [719-832](Homo sapiens (Human))
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM311478(CHEM-US-00184 | US10155764, Example 58)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M67T9US Patent
TargetHistone acetyltransferase KAT2B [719-832](Homo sapiens (Human))
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM311448(CHEM-US-00145 | US10155764, Example 34)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M67T9US Patent
TargetHistone acetyltransferase KAT2B [719-832](Homo sapiens (Human))
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM311497(CHEM-US-00209 | US10155764, Example 74)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M67T9US Patent
TargetHistone acetyltransferase KAT2B [719-832](Homo sapiens (Human))
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM311476(CHEM-US-00182 | US10155764, Example 56)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M67T9US Patent
TargetHistone acetyltransferase KAT2B [719-832](Homo sapiens (Human))
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM311412(US10155764, Example 8A)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M67T9US Patent
TargetHistone acetyltransferase KAT2B [719-832](Homo sapiens (Human))
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM311501(US10155764, Example 76)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M67T9US Patent
TargetHistone acetyltransferase KAT2B [719-832](Homo sapiens (Human))
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM311503(CHEM-US-00222 | US10155764, Example 78)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M67T9US Patent
TargetHistone acetyltransferase KAT2B [719-832](Homo sapiens (Human))
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM311403(US10155764, Example 1A)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M67T9US Patent
TargetHistone acetyltransferase KAT2B [719-832](Homo sapiens (Human))
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM311472(CHEM-US-00174 | US10155764, Example 54 | US1015576...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M67T9US Patent
TargetHistone acetyltransferase KAT2B [719-832](Homo sapiens (Human))
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM311505(CHEM-US-00224 | US10155764, Example 80)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M67T9US Patent
TargetHistone acetyltransferase KAT2B [719-832](Homo sapiens (Human))
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM311433(CHEM-US-00130 | US10155764, Example 22A)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M67T9US Patent
TargetHistone acetyltransferase KAT2B [719-832](Homo sapiens (Human))
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM311510(CHEM-US-00230 | US10155764, Example 85)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M67T9US Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310889(4-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)-N...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 9 [134-239](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310898(N,N-dimethyl-3-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]py...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetBromodomain-containing protein 9 [134-239](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310902(6-methyl-4-[4-(1-methyl-4-piperidyl)phenyl]-1H-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetChromatin remodeling regulator CECR2 [424-538](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310911(6-methyl-4-(2-methyl-3,4-dihydro-1H-isoquinolin-6-...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:His/Flag epitope tagged CECR2424-538 was cloned, expressed, and purified to homogeneity. CECR2 binding and inhibition was assessed by monitoring the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetHistone acetyltransferase KAT2B [719-832](Homo sapiens (Human))
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM311509(CHEM-US-00229 | US10155764, Example 84)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M67T9US Patent
TargetHistone acetyltransferase KAT2B [719-832](Homo sapiens (Human))
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM311424(US10155764, Example 16A)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M67T9US Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310880(7-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)-4...)copy SMILES
Affinity DataIC50: 58nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetHistone acetyltransferase KAT2B [719-832](Homo sapiens (Human))
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM311507(US10155764, Example 82)copy SMILEScopy InChI
Affinity DataIC50: 59nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M67T9US Patent
TargetHistone acetyltransferase KAT2B [719-832](Homo sapiens (Human))
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM311475(US10155764, Example 55)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M67T9US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310915(N-benzyl-4-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetHistone acetyltransferase KAT2B [719-832](Homo sapiens (Human))
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM311482(CHEM-US-00188 | US10155764, Example 62)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M67T9US Patent
TargetBromodomain-containing protein 9 [134-239](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310903(6-methyl-4-[4-[(1-methyl-4-piperidyl)methyl]phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetHistone acetyltransferase KAT2B [719-832](Homo sapiens (Human))
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM311431(CHEM-US-00128 | US10155764, Example 21)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M67T9US Patent
TargetHistone acetyltransferase KAT2B [719-832](Homo sapiens (Human))
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM311440(CHEM-US-00137 | US10155764, Example 28)copy SMILEScopy InChI
Affinity DataIC50: 66nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M67T9US Patent
TargetHistone acetyltransferase KAT2B [719-832](Homo sapiens (Human))
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM311444(CHEM-US-00141 | US10155764, Example 32 | US1015576...)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M67T9US Patent
TargetHistone acetyltransferase KAT2B [719-832](Homo sapiens (Human))
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM311508(CHEM-US-00228 | US10155764, Example 83)copy SMILEScopy InChI
Affinity DataIC50: 71nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M67T9US Patent
TargetHistone acetyltransferase KAT2B [719-832](Homo sapiens (Human))
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM311411(US10155764, Example 7B)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M67T9US Patent
TargetHistone acetyltransferase KAT2B [719-832](Homo sapiens (Human))
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM311504(CHEM-US-00223 | US10155764, Example 79)copy SMILEScopy InChI
Affinity DataIC50: 73nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M67T9US Patent
TargetChromatin remodeling regulator CECR2 [424-538](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310910(4-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)-N...)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:His/Flag epitope tagged CECR2424-538 was cloned, expressed, and purified to homogeneity. CECR2 binding and inhibition was assessed by monitoring the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetHistone acetyltransferase KAT2B [719-832](Homo sapiens (Human))
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM311477(CHEM-US-00183 | US10155764, Example 57)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M67T9US Patent
TargetHistone acetyltransferase KAT2B [719-832](Homo sapiens (Human))
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM311422(US10155764, Example 15A)copy SMILEScopy InChI
Affinity DataIC50: 78nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M67T9US Patent
TargetHistone acetyltransferase KAT2B [719-832](Homo sapiens (Human))
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM311513(US10155764, Example 88)copy SMILES
Affinity DataIC50: 80nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M67T9US Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310879(2-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)-5...)copy SMILES
Affinity DataIC50: 81nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
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