Compile Data Set for Download or QSAR
Found 31 with Last Name = 'hujer' and Initial = 'am'
TargetBeta-lactamase(Escherichia coli)
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50021959(CHEMBL777 | MM 14151 | US9120808, Clavulanic acid ...)copy SMILEScopy InChI
Affinity DataKi:  1.10E+4nMAssay Description:Inhibition of Klebsiella pneumoniae 1534 beta-lactamase KPC-2 by competitive assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7HJPPubMed
TargetBeta-lactamase(Escherichia coli)
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)copy SMILEScopy InChI
Affinity DataKi:  7.40E+4nMAssay Description:Inhibition of Klebsiella pneumoniae 1534 beta-lactamase KPC-2 by competitive assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7HJPPubMed
TargetBeta-lactamase(Escherichia coli)
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50021954((2S,5R)-3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia-...)copy SMILEScopy InChI
Affinity DataKi:  1.67E+5nMAssay Description:Inhibition of Klebsiella pneumoniae 1534 beta-lactamase KPC-2 by competitive assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7HJPPubMed
TargetBeta-lactamase(Enterobacter cloacae)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50157688((5R,6Z)-6-[(7-methylimidazo[2,1-b][1,3]-benzothiaz...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of Enterobacter cloacae AmpCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N22PubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50149467((5R,6Z)-6-(6,7-dihydro-5H-cyclopenta-[d]imidazo[2,...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of Escherichia coli TEM1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N22PubMed
TargetBeta-lactamase(Enterobacter cloacae)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50157689((5R,6Z)-6-(imidazo[2,1-b][1,3]benzothiazol-2-ylmet...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of Enterobacter cloacae AmpCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N22PubMed
TargetBeta-lactamase(Enterobacter cloacae)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50157691((5R,6Z)-6-[(7-methoxyimidazo[2,1-b][1,3]-benzothia...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of Enterobacter cloacae AmpCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N22PubMed
TargetBeta-lactamase(Enterobacter cloacae)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50157687((5R,6Z)-6-[(5-methylimidazo[2,1-b][1,3]-benzothiaz...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of Enterobacter cloacae AmpCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N22PubMed
TargetBeta-lactamase(Enterobacter cloacae)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50149467((5R,6Z)-6-(6,7-dihydro-5H-cyclopenta-[d]imidazo[2,...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of Enterobacter cloacae AmpCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N22PubMed
TargetBeta-lactamase(Enterobacter cloacae)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50157694((5R,6Z)-6-[(7-fluoroimidazo[2,1-b][1,3]-benzothiaz...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of Enterobacter cloacae AmpCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N22PubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50157688((5R,6Z)-6-[(7-methylimidazo[2,1-b][1,3]-benzothiaz...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of Escherichia coli TEM1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N22PubMed
TargetBeta-lactamase(Enterobacter cloacae)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50157693((5R,6Z)-6-[(7-chloroimidazo[2,1-b][1,3]-benzothiaz...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of Enterobacter cloacae AmpCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N22PubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50157693((5R,6Z)-6-[(7-chloroimidazo[2,1-b][1,3]-benzothiaz...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of Escherichia coli TEM1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N22PubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50157694((5R,6Z)-6-[(7-fluoroimidazo[2,1-b][1,3]-benzothiaz...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of Escherichia coli TEM1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N22PubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50157687((5R,6Z)-6-[(5-methylimidazo[2,1-b][1,3]-benzothiaz...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of Escherichia coli TEM1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N22PubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50157689((5R,6Z)-6-(imidazo[2,1-b][1,3]benzothiazol-2-ylmet...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of Escherichia coli TEM1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N22PubMed
TargetBeta-lactamase SHV-1(Klebsiella pneumoniae (Enterobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50149467((5R,6Z)-6-(6,7-dihydro-5H-cyclopenta-[d]imidazo[2,...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of Escherichia coli SHV1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N22PubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50157691((5R,6Z)-6-[(7-methoxyimidazo[2,1-b][1,3]-benzothia...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of Escherichia coli TEM1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N22PubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50157693((5R,6Z)-6-[(7-chloroimidazo[2,1-b][1,3]-benzothiaz...)copy SMILEScopy InChI
Affinity DataIC50: 74nMAssay Description:Inhibition of Bacteroides fragilis CcrAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N22PubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50157692(CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of Escherichia coli TEM1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N22PubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50157688((5R,6Z)-6-[(7-methylimidazo[2,1-b][1,3]-benzothiaz...)copy SMILEScopy InChI
Affinity DataIC50: 103nMAssay Description:Inhibition of Bacteroides fragilis CcrAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N22PubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50149467((5R,6Z)-6-(6,7-dihydro-5H-cyclopenta-[d]imidazo[2,...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of Bacteroides fragilis CcrAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N22PubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50157691((5R,6Z)-6-[(7-methoxyimidazo[2,1-b][1,3]-benzothia...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of Bacteroides fragilis CcrAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N22PubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50157689((5R,6Z)-6-(imidazo[2,1-b][1,3]benzothiazol-2-ylmet...)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibition of Bacteroides fragilis CcrAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N22PubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50157694((5R,6Z)-6-[(7-fluoroimidazo[2,1-b][1,3]-benzothiaz...)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:Inhibition of Bacteroides fragilis CcrAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N22PubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50157687((5R,6Z)-6-[(5-methylimidazo[2,1-b][1,3]-benzothiaz...)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:Inhibition of Bacteroides fragilis CcrAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N22PubMed
TargetPeptidoglycan D,D-transpeptidase FtsI(Pseudomonas aeruginosa)TBA
LigandPNGBDBM50538667(CHEMBL4634190)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Pseudomonas aeruginosa PBP3 assessed as reduction in fluorescence intensity using Bocillin-protein as fluorescent substrate preincubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92G5WPubMed
TargetPeptidoglycan D,D-transpeptidase FtsI(Pseudomonas aeruginosa)TBA
LigandPNGBDBM50538667(CHEMBL4634190)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Pseudomonas aeruginosa PBP3 assessed as reduction in fluorescence intensity of bocillin labeled protein pre-incubated for 20 mins befor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25142S5PubMed
TargetPeptidoglycan D,D-transpeptidase FtsI(Pseudomonas aeruginosa)TBA
LigandPNGBDBM50578473(CHEMBL4872152)copy SMILES
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Pseudomonas aeruginosa PBP3 assessed as reduction in fluorescence intensity using Bocillin-protein as fluorescent substrate preincubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92G5WPubMed
TargetBeta-lactamase(Enterobacter cloacae)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50157692(CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 8.40E+4nMAssay Description:Inhibition of Enterobacter cloacae AmpCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N22PubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50157692(CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of Bacteroides fragilis CcrAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N22PubMed