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Found 114 with Last Name = 'negmeldin' and Initial = 'at'
TargetHistone deacetylase 3(Homo sapiens (Human))
Department of Chemistry, Wayne State University, 5101 Cass Avenue, Detroit, MI 48202, United States.

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of HDAC3 (unknown origin) by ELISA-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3V5JPubMedDrugBank
TargetHistone deacetylase 3(Homo sapiens (Human))
Department of Chemistry, Wayne State University, 5101 Cass Avenue, Detroit, MI 48202, United States.

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of HDAC3 in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 40 mins by fl...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z3228HPubMedDrugBank
TargetHistone deacetylase 3(Homo sapiens (Human))
Department of Chemistry, Wayne State University, 5101 Cass Avenue, Detroit, MI 48202, United States.

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of HDAC3 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TQFPubMedDrugBank
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50550344(CHEMBL4798363)copy SMILES
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) incubated for 15 mins before substrate addition and measured after 30 to 45 mins by HDAC-Glo substra...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VH5SG7PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464530(CHEMBL4287851)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of human recombinant full-length C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cell preincubated for 15 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z3228HPubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Department of Chemistry, Wayne State University, 5101 Cass Avenue, Detroit, MI 48202, United States.

Curated by ChEMBL
LigandPNGBDBM50550344(CHEMBL4798363)copy SMILES
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant HDAC3 (unknown origin)incubated for 15 mins before substrate addition and measured after 30 to 45 mins by HDAC-Glo substrat...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VH5SG7PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50550344(CHEMBL4798363)copy SMILES
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant HDAC2 (unknown origin)incubated for 15 mins before substrate addition and measured after 30 to 45 mins by HDAC-Glo substrat...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VH5SG7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of HDAC6 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TQFPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of HDAC6 in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 40 mins by fl...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z3228HPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of HDAC1 in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 40 mins by fl...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of HDAC6 (unknown origin) by ELISA-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3V5JPubMedDrugBank
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of HDAC1 (unknown origin) by ELISA-based assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of HDAC6 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TQFPubMedDrugBank
TargetHistone deacetylase 6(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of HDAC6 in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 40 mins by fl...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z3228HPubMedDrugBank
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of HDAC1 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM19423(HDAC inhibitor, Compound 1 | N-[2-amino-5-(thiophe...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of wild-type FLAG-tagged HDAC1 (unknown origin) expressed in Jurkat cells after 2 hrs by Fluor de lys staining-based fluorimetric analysisMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464530(CHEMBL4287851)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibition of HDAC6 in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 40 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z3228HPubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Department of Chemistry, Wayne State University, 5101 Cass Avenue, Detroit, MI 48202, United States.

Curated by ChEMBL
LigandPNGBDBM50322422(CHEMBL1173445 | Largazole)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant HDAC3 (unknown origin)incubated for 15 mins before substrate addition and measured after 30 to 45 mins by HDAC-Glo substrat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VH5SG7PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464529(CHEMBL4284448)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibition of human recombinant full-length C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cell preincubated for 15 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z3228HPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50322422(CHEMBL1173445 | Largazole)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) incubated for 15 mins before substrate addition and measured after 30 to 45 mins by HDAC-Glo substra...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VH5SG7PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50322422(CHEMBL1173445 | Largazole)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Inhibition of recombinant HDAC2 (unknown origin)incubated for 15 mins before substrate addition and measured after 30 to 45 mins by HDAC-Glo substrat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VH5SG7PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464527(CHEMBL4285869)copy SMILEScopy InChI
Affinity DataIC50: 74nMAssay Description:Inhibition of human recombinant full-length C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cell preincubated for 15 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z3228HPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464534(CHEMBL4277951)copy SMILEScopy InChI
Affinity DataIC50: 79nMAssay Description:Inhibition of human recombinant full-length C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cell preincubated for 15 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z3228HPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464527(CHEMBL4285869)copy SMILEScopy InChI
Affinity DataIC50: 88nMAssay Description:Inhibition of HDAC6 in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 40 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z3228HPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464528(CHEMBL4283418)copy SMILEScopy InChI
Affinity DataIC50: 95nMAssay Description:Inhibition of HDAC6 in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 40 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z3228HPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))TBA
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 96nMAssay Description:Inhibition of HDAC2 in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 40 mins by fl...More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))TBA
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 96nMAssay Description:Inhibition of HDAC2 (unknown origin) by ELISA-based assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))TBA
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 96nMAssay Description:Inhibition of HDAC2 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464532(CHEMBL4295105)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of HDAC6 in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 40 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z3228HPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464531(CHEMBL4288220)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant full-length C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cell preincubated for 15 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z3228HPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464534(CHEMBL4277951)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of HDAC6 in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 40 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z3228HPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464529(CHEMBL4284448)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of HDAC6 in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 40 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z3228HPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464528(CHEMBL4283418)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant full-length C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cell preincubated for 15 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z3228HPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464531(CHEMBL4288220)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of HDAC6 in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 40 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z3228HPubMed
TargetHistone deacetylase(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of HDAC in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 35 mins by fluorimet...More data for this Ligand-Target Pair
TargetHistone deacetylase(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM19423(HDAC inhibitor, Compound 1 | N-[2-amino-5-(thiophe...)copy SMILEScopy InChI
Affinity DataIC50: 204nMAssay Description:Inhibition of FLAG-tagged HDAC1 S113A mutant (unknown origin) expressed in Jurkat cells after 2 hrs by Fluor de lys staining-based fluorimetric analy...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50268604(CHEMBL4102833)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Inhibition of HDAC6 (unknown origin) by ELISA-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3V5JPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464532(CHEMBL4295105)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Inhibition of human recombinant full-length C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cell preincubated for 15 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z3228HPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50268605(CHEMBL4086409)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Inhibition of HDAC6 (unknown origin) by ELISA-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3V5JPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Inhibition of full length human C-terminal His-tag HDAC8 expressed in baculovirus expression system preincubated for 15 mins followed by HDAC-Glo sub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TQFPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Inhibition of human recombinant full-length C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cell preincubated for 15 mins fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z3228HPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50268604(CHEMBL4102833)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Inhibition of HDAC8 (unknown origin) by ELISA-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3V5JPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50268603(CHEMBL4064944)copy SMILEScopy InChI
Affinity DataIC50: 410nMAssay Description:Inhibition of HDAC6 (unknown origin) by ELISA-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3V5JPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50268603(CHEMBL4064944)copy SMILEScopy InChI
Affinity DataIC50: 420nMAssay Description:Inhibition of HDAC8 (unknown origin) by ELISA-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3V5JPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50268605(CHEMBL4086409)copy SMILEScopy InChI
Affinity DataIC50: 430nMAssay Description:Inhibition of HDAC8 (unknown origin) by ELISA-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3V5JPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 540nMAssay Description:Inhibition of human recombinant full-length C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cell preincubated for 15 mins fo...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 540nMAssay Description:Inhibition of full length human C-terminal His-tag HDAC8 expressed in baculovirus expression system preincubated for 15 mins followed by HDAC-Glo sub...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 540nMAssay Description:Inhibition of HDAC8 (unknown origin) by ELISA-based assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212243(CHEMBL3982264)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibition of HDAC6 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TQFPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212247(CHEMBL3982065)copy SMILEScopy InChI
Affinity DataIC50: 710nMAssay Description:Inhibition of full length human C-terminal His-tag HDAC8 expressed in baculovirus expression system preincubated for 15 mins followed by HDAC-Glo sub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TQFPubMed
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