Compile Data Set for Download or QSAR
Found 43 with Last Name = 'pagarigan' and Initial = 'b'
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50512318(CHEMBL4546504)copy SMILEScopy InChI
Affinity DataIC50: 0.00100nMAssay Description:Inhibition of recombinant human GST-tagged LRRK2 G2019S mutant catalytic domain (970 to 2527 residues) expressed in baculovirus expression system usi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6VVNPubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50512318(CHEMBL4546504)copy SMILEScopy InChI
Affinity DataIC50: 0.00100nMAssay Description:Inhibition of recombinant human GST-tagged LRRK2 catalytic domain (970 to 2527 residues) expressed in baculovirus expression system using LRRKtide as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6VVNPubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50512318(CHEMBL4546504)copy SMILEScopy InChI
Affinity DataIC50: 0.0320nMAssay Description:Inhibition of recombinant human full length His-tagged JNK1 expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6VVNPubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50512318(CHEMBL4546504)copy SMILEScopy InChI
Affinity DataIC50: 0.0590nMAssay Description:Inhibition of recombinant human full length His-tagged JNK2 expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6VVNPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 3(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50512318(CHEMBL4546504)copy SMILEScopy InChI
Affinity DataIC50: 0.104nMAssay Description:Inhibition of recombinant human full length GST-tagged DYRK3 expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6VVNPubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50512318(CHEMBL4546504)copy SMILEScopy InChI
Affinity DataIC50: 0.107nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged JNK3 expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6VVNPubMed
TargetTestis-specific serine/threonine-protein kinase 1(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50512318(CHEMBL4546504)copy SMILEScopy InChI
Affinity DataIC50: 0.217nMAssay Description:Inhibition of recombinant human full length His-tagged TSSK1 expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6VVNPubMed
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50512318(CHEMBL4546504)copy SMILEScopy InChI
Affinity DataIC50: 0.261nMAssay Description:Inhibition of recombinant human GST-tagged CLK2 catalytic domain (137 to 498 residues) expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6VVNPubMed
TargetLeukocyte tyrosine kinase receptor(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50512318(CHEMBL4546504)copy SMILEScopy InChI
Affinity DataIC50: 0.567nMAssay Description:Inhibition of recombinant human GST-tagged LTK cytoplasmic domain (450 to 864 residues) expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6VVNPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50512326(CHEMBL4476012)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Kinase Tracer 236 binding to recombinant human full-length GST-tagged TTk expressed in baculovirus expression system measured after 1 h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6VVNPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50512318(CHEMBL4546504)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of Kinase Tracer 236 binding to recombinant human full-length GST-tagged TTk expressed in baculovirus expression system measured after 1 h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50512322(CHEMBL4450891)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of Kinase Tracer 236 binding to recombinant human full-length GST-tagged TTk expressed in baculovirus expression system measured after 1 h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6VVNPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50512321(CHEMBL4472951)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of Kinase Tracer 236 binding to recombinant human full-length GST-tagged TTk expressed in baculovirus expression system measured after 1 h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6VVNPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50512323(CHEMBL4558047)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of Kinase Tracer 236 binding to recombinant human full-length GST-tagged TTk expressed in baculovirus expression system measured after 1 h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6VVNPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50512325(CHEMBL4585148)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of Kinase Tracer 236 binding to recombinant human full-length GST-tagged TTk expressed in baculovirus expression system measured after 1 h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6VVNPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50512324(CHEMBL4521278)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of Kinase Tracer 236 binding to recombinant human full-length GST-tagged TTk expressed in baculovirus expression system measured after 1 h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6VVNPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50512316(CHEMBL4530475)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of Kinase Tracer 236 binding to recombinant human full-length GST-tagged TTk expressed in baculovirus expression system measured after 1 h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6VVNPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50512317(CHEMBL4569626)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of Kinase Tracer 236 binding to recombinant human full-length GST-tagged TTk expressed in baculovirus expression system measured after 1 h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6VVNPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50512320(CHEMBL4467041)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of Kinase Tracer 236 binding to recombinant human full-length GST-tagged TTk expressed in baculovirus expression system measured after 1 h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6VVNPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM317462(4-(4-(cyclopentyloxy)-5-(2- methylbenzo[d]oxazol-6...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human full length recombinant GST-tagged TTK expressed in baculovirus by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM317462(4-(4-(cyclopentyloxy)-5-(2- methylbenzo[d]oxazol-6...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human GST-tagged CLK2 expressed in baculovirus by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0WX9PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50512319(CHEMBL4547530)copy SMILEScopy InChI
Affinity DataIC50: 7.20nMAssay Description:Inhibition of Kinase Tracer 236 binding to recombinant human full-length GST-tagged TTk expressed in baculovirus expression system measured after 1 h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6VVNPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50512318(CHEMBL4546504)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of TTK autophosphorylation in human CAL51 cells by radioimmuno-precipitation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50512318(CHEMBL4546504)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of TTK in human CAL51 cells assessed as decrease in phosphorylated TTK T686 levels after 1 hr by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM317462(4-(4-(cyclopentyloxy)-5-(2- methylbenzo[d]oxazol-6...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of CLK2 in human HCT116 cell lysate after 1 hr by LC-MS/MS analysis relative to controlMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0WX9PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50512324(CHEMBL4521278)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of TTK autophosphorylation in human CAL51 cells by radioimmuno-precipitation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6VVNPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50512318(CHEMBL4546504)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of TTK in human CAL51 cells assessed as decrease in phosphorylated KNL-1 T943 levels after 1 hr by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50512317(CHEMBL4569626)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of TTK autophosphorylation in human CAL51 cells by radioimmuno-precipitation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6VVNPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM317462(4-(4-(cyclopentyloxy)-5-(2- methylbenzo[d]oxazol-6...)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibition of TTK in human CAL51 cells assessed as decrease in phosphorylated TTK T686 levels after 1 hr by Western blot analysisMore data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM317462(4-(4-(cyclopentyloxy)-5-(2- methylbenzo[d]oxazol-6...)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibition of TTK phosphorylation at T686 residue in human CAL51 cells after 1 hr by Western blot analysisMore data for this Ligand-Target Pair
TargetDNA damage-binding protein 1/Protein cereblon(Homo sapiens (Human))
Celgene Corporation

LigandPNGBDBM65497(CC-220 (Compound 6) | US9694015, 6.4S)copy SMILEScopy InChI
Affinity DataIC50: 60nMpH: 7.0Assay Description:The 6XHis-tagged full length human CRBN bound to full length human DDB1 used in the assay was purified as described elsewhere with the exception that...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 3(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM317462(4-(4-(cyclopentyloxy)-5-(2- methylbenzo[d]oxazol-6...)copy SMILEScopy InChI
Affinity DataIC50: 99nMAssay Description:Inhibition of human full length recombinant GST-tagged DYRK3 expressed in baculovirus by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0WX9PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM317462(4-(4-(cyclopentyloxy)-5-(2- methylbenzo[d]oxazol-6...)copy SMILEScopy InChI
Affinity DataIC50: 104nMAssay Description:Inhibition of human full length GST-tagged DYRK1A expressed in baculovirus by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0WX9PubMed
TargetPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM317462(4-(4-(cyclopentyloxy)-5-(2- methylbenzo[d]oxazol-6...)copy SMILEScopy InChI
Affinity DataIC50: 136nMAssay Description:Inhibition of full length human GST-tagged PHKG1 expressed in baculovirus by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0WX9PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM317462(4-(4-(cyclopentyloxy)-5-(2- methylbenzo[d]oxazol-6...)copy SMILEScopy InChI
Affinity DataIC50: 157nMAssay Description:Inhibition of full length human recombinant GST-tagged DYRK1B expressed in baculovirus by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0WX9PubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM317462(4-(4-(cyclopentyloxy)-5-(2- methylbenzo[d]oxazol-6...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of human GST-tagged CLK1 expressed in Escherichia coli by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0WX9PubMed
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM317462(4-(4-(cyclopentyloxy)-5-(2- methylbenzo[d]oxazol-6...)copy SMILEScopy InChI
Affinity DataIC50: 549nMAssay Description:Inhibition of CLK2 in human CAL51 cells assessed as reduction in phosphorylation of SRp75 after 1 hr by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0WX9PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM317462(4-(4-(cyclopentyloxy)-5-(2- methylbenzo[d]oxazol-6...)copy SMILEScopy InChI
Affinity DataIC50: 680nMAssay Description:Inhibition of CAMKK2 in human HCT116 cell lysate after 1 hr by LC-MS/MS analysis relative to controlMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0WX9PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM317462(4-(4-(cyclopentyloxy)-5-(2- methylbenzo[d]oxazol-6...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of PIP4K2C in human HCT116 cell lysate after 1 hr by LC-MS/MS analysis relative to controlMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0WX9PubMed
TargetDNA damage-binding protein 1/Protein cereblon(Homo sapiens (Human))
Celgene Corporation

LigandPNGBDBM65456(19171-19-8 | 4-amino-2-(2,6-dioxopiperidin-3-yl)is...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMpH: 7.0Assay Description:The 6XHis-tagged full length human CRBN bound to full length human DDB1 used in the assay was purified as described elsewhere with the exception that...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC30HGPubMed
TargetMitogen-activated protein kinase 10/8/9(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM317462(4-(4-(cyclopentyloxy)-5-(2- methylbenzo[d]oxazol-6...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of JNK1/JNK2/JNK3 in human HCT116 cell lysate after 1 hr by LC-MS/MS analysis relative to controlMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0WX9PubMed
TargetDNA damage-binding protein 1/Protein cereblon(Homo sapiens (Human))
Celgene Corporation

LigandPNGBDBM65454(191732-72-6 | CC-5013 | Lenalidomide | Revimid | R...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMpH: 7.0Assay Description:The 6XHis-tagged full length human CRBN bound to full length human DDB1 used in the assay was purified as described elsewhere with the exception that...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM317462(4-(4-(cyclopentyloxy)-5-(2- methylbenzo[d]oxazol-6...)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0WX9PubMed