Compile Data Set for Download or QSAR
Found 28 with Last Name = 'debrosse' and Initial = 'c'
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074035(CHEMBL82980 | {7-[(4-Carbamimidoyl-phenyl)-methyl-...)copy SMILEScopy InChI
Affinity DataKi:  1.5nMAssay Description:Fibrinogen receptor binding affinity was determined by assaying for inhibition of [3H]-1 binding to purified Fibrinogen Receptor isolated from human...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ295HPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50054827(CHEMBL85094 | SB-208651 | {8-[(4-Carbamimidoyl-phe...)copy SMILEScopy InChI
Affinity DataKi:  1.60nMAssay Description:Fibrinogen receptor binding affinity was determined by assaying for inhibition of [3H]-1 binding to purified Fibrinogen Receptor isolated from human...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ295HPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074030(CHEMBL356020 | {8-[Methyl-(2-piperidin-4-yl-ethyl)...)copy SMILEScopy InChI
Affinity DataKi:  1.90nMAssay Description:Fibrinogen receptor binding affinity was determined by assaying for inhibition of [3H]-1 binding to purified Fibrinogen Receptor isolated from human...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ295HPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074029(CHEMBL153162 | [8-(4-Carbamimidoyl-benzoylamino)-3...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Fibrinogen receptor binding affinity was determined by assaying for inhibition of [3H]-1 binding to purified Fibrinogen Receptor isolated from human...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ295HPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074044(CHEMBL152156 | [(S)-8-(4-Carbamimidoyl-phenylcarba...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Fibrinogen receptor binding affinity was determined by assaying for inhibition of [3H]-1 binding to purified Fibrinogen Receptor isolated from human...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ295HPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036089(CHEMBL18288 | [8-(4-Carbamimidoyl-phenylcarbamoyl)...)copy SMILEScopy InChI
Affinity DataKi:  2.80nMAssay Description:Fibrinogen receptor binding affinity was determined by assaying for inhibition of [3H]-1 binding to purified Fibrinogen Receptor isolated from human...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ295HPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074033(CHEMBL151190 | [3-Oxo-4-phenethyl-8-(2-piperidin-4...)copy SMILEScopy InChI
Affinity DataKi:  4.70nMAssay Description:Fibrinogen receptor binding affinity was determined by assaying for inhibition of [3H]-1 binding to purified Fibrinogen Receptor isolated from human...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ295HPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074031(CHEMBL153802 | [3-Oxo-4-phenethyl-8-((E)-4-piperid...)copy SMILEScopy InChI
Affinity DataKi:  19nMAssay Description:Fibrinogen receptor binding affinity was determined by assaying for inhibition of [3H]-1 binding to purified Fibrinogen Receptor isolated from human...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ295HPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074039(CHEMBL265798 | [3-Oxo-4-phenethyl-8-(4-piperidin-4...)copy SMILEScopy InChI
Affinity DataKi:  80nMAssay Description:Fibrinogen receptor binding affinity was determined by assaying for inhibition of [3H]-1 binding to purified Fibrinogen Receptor isolated from human...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ295HPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074042(3-[7-(4-Carbamimidoyl-benzoylamino)-3-oxo-1,2,3,5-...)copy SMILEScopy InChI
Affinity DataKi:  290nMAssay Description:Fibrinogen receptor binding affinity was determined by assaying for inhibition of [3H]-1 binding to purified Fibrinogen Receptor isolated from human...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ295HPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074047(CHEMBL153083 | [(R)-8-(4-Carbamimidoyl-phenylcarba...)copy SMILEScopy InChI
Affinity DataKi:  500nMAssay Description:Fibrinogen receptor binding affinity was determined by assaying for inhibition of [3H]-1 binding to purified Fibrinogen Receptor isolated from human...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ295HPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074034(CHEMBL152648 | [8-(4-Carbamimidoyl-phenylcarbamoyl...)copy SMILEScopy InChI
Affinity DataKi:  540nMAssay Description:Fibrinogen receptor binding affinity was determined by assaying for inhibition of [3H]-1 binding to purified Fibrinogen Receptor isolated from human...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ295HPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074046(2-[3-(4-Carbamimidoyl-phenylcarbamoyl)-phenylamino...)copy SMILEScopy InChI
Affinity DataKi:  560nMAssay Description:Fibrinogen receptor binding affinity was determined by assaying for inhibition of [3H]-1 binding to purified Fibrinogen Receptor isolated from human...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ295HPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074043(CHEMBL152015 | [3-Oxo-4-phenethyl-8-((Z)-4-piperid...)copy SMILEScopy InChI
Affinity DataKi:  750nMAssay Description:Fibrinogen receptor binding affinity was determined by assaying for inhibition of [3H]-1 binding to purified Fibrinogen Receptor isolated from human...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ295HPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074045(CHEMBL435833 | [8-(4-Carbamimidoyl-phenylcarbamoyl...)copy SMILEScopy InChI
Affinity DataKi:  800nMAssay Description:Fibrinogen receptor binding affinity was determined by assaying for inhibition of [3H]-1 binding to purified Fibrinogen Receptor isolated from human...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ295HPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074040(CHEMBL154864 | [7-(4-Carbamimidoyl-benzoylamino)-3...)copy SMILEScopy InChI
Affinity DataKi:  1.20E+3nMAssay Description:Fibrinogen receptor binding affinity was determined by assaying for inhibition of [3H]-1 binding to purified Fibrinogen Receptor isolated from human...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ295HPubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50042185(4,5-Bis-benzo[1,3]dioxol-5-ylmethyl-1-methyl-1H-im...)copy SMILEScopy InChI
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K28K5PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074036(CHEMBL356819 | [8-(4-Carbamimidoyl-phenylcarbamoyl...)copy SMILEScopy InChI
Affinity DataKi:  1.50E+3nMAssay Description:Fibrinogen receptor binding affinity was determined by assaying for inhibition of [3H]-1 binding to purified Fibrinogen Receptor isolated from human...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ295HPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074037(CHEMBL152786 | [8-(4-Carbamimidoyl-benzoylamino)-3...)copy SMILEScopy InChI
Affinity DataKi:  1.75E+3nMAssay Description:Fibrinogen receptor binding affinity was determined by assaying for inhibition of [3H]-1 binding to purified Fibrinogen Receptor isolated from human...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ295HPubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292405(CHEMBL485054 | leucettamidine)copy SMILEScopy InChI
Affinity DataKi:  5.30E+3nMAssay Description:Displacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K28K5PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074041(CHEMBL152354 | [8-(4-Carbamimidoyl-benzoylamino)-5...)copy SMILEScopy InChI
Affinity DataKi:  1.49E+4nMAssay Description:Fibrinogen receptor binding affinity was determined by assaying for inhibition of [3H]-1 binding to purified Fibrinogen Receptor isolated from human...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ295HPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074038(3-{8-[(4-Carbamimidoyl-phenyl)-methyl-carbamoyl]-3...)copy SMILEScopy InChI
Affinity DataKi:  2.25E+4nMAssay Description:Fibrinogen receptor binding affinity was determined by assaying for inhibition of [3H]-1 binding to purified Fibrinogen Receptor isolated from human...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ295HPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074032(CHEMBL358645 | {8-[(4-Carbamimidoyl-phenyl)-methyl...)copy SMILEScopy InChI
Affinity DataKi: >5.00E+4nMAssay Description:Fibrinogen receptor binding affinity was determined by assaying for inhibition of [3H]-1 binding to purified Fibrinogen Receptor isolated from human...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ295HPubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292406(CHEMBL485053 | leucettamine B)copy SMILEScopy InChI
Affinity DataKi:  1.00E+5nMAssay Description:Displacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K28K5PubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50042185(4,5-Bis-benzo[1,3]dioxol-5-ylmethyl-1-methyl-1H-im...)copy SMILEScopy InChI
Affinity DataIC50: 750nMAssay Description:Binding affinity to LTB4 receptor in human U937 cells by whole cell assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K28K5PubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50042185(4,5-Bis-benzo[1,3]dioxol-5-ylmethyl-1-methyl-1H-im...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Displacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K28K5PubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50042185(4,5-Bis-benzo[1,3]dioxol-5-ylmethyl-1-methyl-1H-im...)copy SMILEScopy InChI
Affinity DataIC50: 4.60E+3nMAssay Description:Antagonist activity at LTB4 receptor in fura-2 loaded human U937 cells assessed as inhibition of LTB4-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K28K5PubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292405(CHEMBL485054 | leucettamidine)copy SMILEScopy InChI
Affinity DataIC50: 1.56E+4nMAssay Description:Displacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K28K5PubMed