Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Integrin alpha-IIb/beta-3' and Ligand = 'BDBM50036089'
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036089(CHEMBL18288 | [8-(4-Carbamimidoyl-phenylcarbamoyl)...)copy SMILEScopy InChI
Affinity DataKi:  2.30nMAssay Description:Inhibition of [3H]-SKF- 107260 binding to purified alphaIIb-beta3 integrin of human plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PN94PDPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036089(CHEMBL18288 | [8-(4-Carbamimidoyl-phenylcarbamoyl)...)copy SMILEScopy InChI
Affinity DataKi:  2.80nMAssay Description:Fibrinogen receptor binding affinity was determined by assaying for inhibition of [3H]-1 binding to purified Fibrinogen Receptor isolated from human...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ295HPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036089(CHEMBL18288 | [8-(4-Carbamimidoyl-phenylcarbamoyl)...)copy SMILEScopy InChI
Affinity DataKi:  2.80nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M65Q4
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036089(CHEMBL18288 | [8-(4-Carbamimidoyl-phenylcarbamoyl)...)copy SMILEScopy InChI
Affinity DataKi:  2.80nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9H16PubMed