TargetCaspase-3(Homo sapiens (Human))
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataKi: 0.240nMAssay Description:Displacement of [125I]ET1 from endothelin A receptor in DBA mouse microsomesMore data for this Ligand-Target Pair
Affinity DataKi: 0.360nMAssay Description:Displacement of [125I]ET1 from endothelin A receptor in DBA mouse microsomesMore data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataKi: 1.09nMAssay Description:Displacement of [125I]ET1 from endothelin A receptor in DBA mouse microsomesMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [125I]ET1 from ETA receptor in CD1 Nu/Nu mouse myocardial ventricles membranes after 2 hrs by gamma countingMore data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataKi: 1.26nMAssay Description:Displacement of [125I]ET1 from endothelin A receptor in DBA mouse microsomesMore data for this Ligand-Target Pair
Affinity DataKi: 1.26nMAssay Description:Displacement of [125I]ET1 from endothelin B receptor in DBA mouse microsomesMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Displacement of [125I]ET1 from ETA receptor in CD1 Nu/Nu mouse myocardial ventricles membranes after 2 hrs by gamma countingMore data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Displacement of [125I]ET1 from ETA receptor in CD1 Nu/Nu mouse myocardial ventricles membranes after 2 hrs by gamma countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.43nMAssay Description:Displacement of [125I]ET1 from endothelin A receptor in DBA mouse microsomesMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Displacement of [125I]ET1 from ETA receptor in CD1 Nu/Nu mouse myocardial ventricles membranes after 2 hrs by gamma countingMore data for this Ligand-Target Pair
Affinity DataKi: 3.90nMAssay Description:Displacement of [125I]ET1 from ETA receptor in CD1 Nu/Nu mouse myocardial ventricles membranes after 2 hrs by gamma countingMore data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:Displacement of [125I]ET1 from ETA receptor in CD1 Nu/Nu mouse myocardial ventricles membranes after 2 hrs by gamma countingMore data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
Affinity DataKi: 4.80nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
Affinity DataKi: 5.90nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataKi: 7.30nMAssay Description:Displacement of [125I]ET1 from ETA receptor in CD1 Nu/Nu mouse myocardial ventricles membranes after 2 hrs by gamma countingMore data for this Ligand-Target Pair
Affinity DataKi: 7.90nMAssay Description:Displacement of [125I]ET1 from ETA receptor in CD1 Nu/Nu mouse myocardial ventricles membranes after 2 hrs by gamma countingMore data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
Affinity DataKi: 8.30nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
Affinity DataKi: 8.60nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
Affinity DataKi: 9nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
Affinity DataKi: 9.80nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
Affinity DataKi: 12.6nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
Affinity DataKi: 12.6nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
Affinity DataKi: 17.9nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
Affinity DataKi: 23.5nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Displacement of [125I]ET1 from endothelin A receptor in DBA mouse microsomesMore data for this Ligand-Target Pair
Affinity DataKi: 37nMAssay Description:Displacement of [125I]ET1 from ETB receptor in CD1 Nu/Nu mouse myocardial ventricles membranes after 2 hrs by gamma countingMore data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
Affinity DataKi: 41.8nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
Affinity DataKi: 56.1nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataKi: 72nMAssay Description:Displacement of [125I]ET1 from endothelin B receptor in DBA mouse microsomesMore data for this Ligand-Target Pair
Affinity DataKi: 96nMAssay Description:Displacement of [125I]ET1 from endothelin B receptor in DBA mouse microsomesMore data for this Ligand-Target Pair
Affinity DataKi: 98nMAssay Description:Displacement of [125I]ET1 from endothelin B receptor in DBA mouse microsomesMore data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Displacement of [125I]ET1 from endothelin B receptor in DBA mouse microsomesMore data for this Ligand-Target Pair
Affinity DataKi: 240nMAssay Description:Displacement of [125I]ET1 from endothelin B receptor in DBA mouse microsomesMore data for this Ligand-Target Pair
Affinity DataKi: 240nMAssay Description:Displacement of [125I]ET1 from ETB receptor in CD1 Nu/Nu mouse myocardial ventricles membranes after 2 hrs by gamma countingMore data for this Ligand-Target Pair
Affinity DataKi: 288nMAssay Description:Displacement of [125I]ET1 from ETB receptor in CD1 Nu/Nu mouse myocardial ventricles membranes after 2 hrs by gamma countingMore data for this Ligand-Target Pair
Affinity DataKi: 418nMAssay Description:Displacement of [125I]ET1 from ETB receptor in CD1 Nu/Nu mouse myocardial ventricles membranes after 2 hrs by gamma countingMore data for this Ligand-Target Pair
Affinity DataKi: 893nMAssay Description:Displacement of [125I]ET1 from ETB receptor in CD1 Nu/Nu mouse myocardial ventricles membranes after 2 hrs by gamma countingMore data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataKi: 5.34E+3nMAssay Description:Displacement of [125I]ET1 from ETB receptor in CD1 Nu/Nu mouse myocardial ventricles membranes after 2 hrs by gamma countingMore data for this Ligand-Target Pair
Affinity DataKi: 6.45E+3nMAssay Description:Displacement of [125I]ET1 from ETB receptor in CD1 Nu/Nu mouse myocardial ventricles membranes after 2 hrs by gamma countingMore data for this Ligand-Target Pair
Affinity DataKi: 8.45E+3nMAssay Description:Displacement of [125I]ET1 from ETB receptor in CD1 Nu/Nu mouse myocardial ventricles membranes after 2 hrs by gamma countingMore data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of caspase 3More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Displacement of [125I]ET1 from endothelin A receptor in DBA mouse microsomesMore data for this Ligand-Target Pair