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Found 112 with Last Name = 'rademacher' and Initial = 'c'
TargetMyelin-associated glycoprotein(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50354062(CHEMBL1836190)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of MAG -Fc chimera expressed in CHO cells using NeuAc alpha2-3Galbeta1-4GlcNAc-R coupled biotinylated polyacrylamide after 30 mins by ELIS...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD40ZWPubMed
LigandPNGBDBM50556732(CHEMBL4750435)copy SMILES
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171QPPubMed
LigandPNGBDBM50342004(4-(2-(3-(4-nitrophenyl)-5-oxo-1-phenyl-1H-pyrazol-...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171QPPubMed
LigandPNGBDBM50556755(CHEMBL4763014)copy SMILES
Affinity DataIC50: 65nMAssay Description:Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171QPPubMed
LigandPNGBDBM50556754(CHEMBL4781443)copy SMILES
Affinity DataIC50: 75nMAssay Description:Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171QPPubMed
TargetMyelin-associated glycoprotein(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50354056(CHEMBL1836336)copy SMILEScopy InChI
Affinity DataIC50: 79nMAssay Description:Inhibition of MAG -Fc chimera expressed in CHO cells using NeuAc alpha2-3Galbeta1-4GlcNAc-R coupled biotinylated polyacrylamide after 30 mins by ELIS...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD40ZWPubMed
LigandPNGBDBM50556737(CHEMBL4742016)copy SMILES
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171QPPubMed
LigandPNGBDBM50556732(CHEMBL4750435)copy SMILES
Affinity DataIC50: 130nMAssay Description:Inhibition of PTPN7 (unknown origin) pre-incubated for 20 mins followed by fluorescence substrate addition and measured after 120 mins by DiFMUP assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171QPPubMed
LigandPNGBDBM50556732(CHEMBL4750435)copy SMILES
Affinity DataIC50: 130nMAssay Description:Inhibition of PTPN6 (unknown origin) pre-incubated for 20 mins followed by fluorescence substrate addition and measured after 120 mins by DiFMUP assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171QPPubMed
LigandPNGBDBM50556733(CHEMBL4755222)copy SMILES
Affinity DataIC50: 130nMAssay Description:Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171QPPubMed
LigandPNGBDBM50556732(CHEMBL4750435)copy SMILES
Affinity DataIC50: 130nMAssay Description:Inhibition of PTPN12 (unknown origin) pre-incubated for 20 mins followed by fluorescence substrate addition and measured after 120 mins by DiFMUP ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171QPPubMed
LigandPNGBDBM50556748(CHEMBL4741433)copy SMILES
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171QPPubMed
LigandPNGBDBM50556732(CHEMBL4750435)copy SMILES
Affinity DataIC50: 200nMAssay Description:Inhibition of PP2A alpha (unknown origin) pre-incubated for 20 mins followed by fluorescence substrate addition and measured after 120 mins by DiFMUP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171QPPubMed
LigandPNGBDBM50556735(CHEMBL4747136)copy SMILES
Affinity DataIC50: 240nMAssay Description:Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171QPPubMed
TargetMyelin-associated glycoprotein(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50354049(CHEMBL1836306)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of MAGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD40ZWPubMed
TargetMyelin-associated glycoprotein(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50354061(CHEMBL1836340)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of MAG -Fc chimera expressed in CHO cells using NeuAc alpha2-3Galbeta1-4GlcNAc-R coupled biotinylated polyacrylamide after 30 mins by ELIS...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD40ZWPubMed
LigandPNGBDBM50556743(CHEMBL4783825)copy SMILES
Affinity DataIC50: 390nMAssay Description:Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171QPPubMed
LigandPNGBDBM50342003(CHEMBL501993 | NSC-87877 | disodium 8-hydroxy-7-[(...)copy SMILEScopy InChI
Affinity DataIC50: 410nMAssay Description:Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171QPPubMed
LigandPNGBDBM50556736(CHEMBL4749307)copy SMILES
Affinity DataIC50: 410nMAssay Description:Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171QPPubMed
LigandPNGBDBM50556734(CHEMBL4795725)copy SMILES
Affinity DataIC50: 410nMAssay Description:Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171QPPubMed
LigandPNGBDBM50556732(CHEMBL4750435)copy SMILES
Affinity DataIC50: 410nMAssay Description:Inhibition of PTPN1 (unknown origin) pre-incubated for 20 mins followed by fluorescence substrate addition and measured after 120 mins by DiFMUP assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171QPPubMed
LigandPNGBDBM50556730(CHEMBL4777804)copy SMILES
Affinity DataIC50: 580nMAssay Description:Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 20 uM DiFMUP by DiFMUP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171QPPubMed
TargetMyelin-associated glycoprotein(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50354055(CHEMBL1836335)copy SMILEScopy InChI
Affinity DataIC50: 610nMAssay Description:Inhibition of MAG -Fc chimera expressed in CHO cells using NeuAc alpha2-3Galbeta1-4GlcNAc-R coupled biotinylated polyacrylamide after 30 mins by ELIS...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD40ZWPubMed
TargetMyelin-associated glycoprotein(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50354058(CHEMBL1836337)copy SMILEScopy InChI
Affinity DataIC50: 640nMAssay Description:Inhibition of MAG -Fc chimera expressed in CHO cells using NeuAc alpha2-3Galbeta1-4GlcNAc-R coupled biotinylated polyacrylamide after 30 mins by ELIS...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD40ZWPubMed
TargetMyelin-associated glycoprotein(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50354054(CHEMBL1836334)copy SMILEScopy InChI
Affinity DataIC50: 650nMAssay Description:Inhibition of MAG -Fc chimera expressed in CHO cells using NeuAc alpha2-3Galbeta1-4GlcNAc-R coupled biotinylated polyacrylamide after 30 mins by ELIS...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD40ZWPubMed
TargetMyelin-associated glycoprotein(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50354060(CHEMBL1836339)copy SMILEScopy InChI
Affinity DataIC50: 750nMAssay Description:Inhibition of MAG -Fc chimera expressed in CHO cells using NeuAc alpha2-3Galbeta1-4GlcNAc-R coupled biotinylated polyacrylamide after 30 mins by ELIS...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD40ZWPubMed
TargetMyelin-associated glycoprotein(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50354059(CHEMBL1836338)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of MAG -Fc chimera expressed in CHO cells using NeuAc alpha2-3Galbeta1-4GlcNAc-R coupled biotinylated polyacrylamide after 30 mins by ELIS...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD40ZWPubMed
LigandPNGBDBM50556745(CHEMBL4753055)copy SMILES
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171QPPubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))TBA
LigandPNGBDBM50556732(CHEMBL4750435)copy SMILES
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of PTPRC (unknown origin) pre-incubated for 20 mins followed by fluorescence substrate addition and measured after 120 mins by DiFMUP assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171QPPubMed
TargetMyelin-associated glycoprotein(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50354053(CHEMBL1836313)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of MAG -Fc chimera expressed in CHO cells using NeuAc alpha2-3Galbeta1-4GlcNAc-R coupled biotinylated polyacrylamide after 30 mins by ELIS...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD40ZWPubMed
TargetMyelin-associated glycoprotein(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50354050(CHEMBL1836310)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of MAGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD40ZWPubMed
LigandPNGBDBM50556746(CHEMBL4752755)copy SMILES
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171QPPubMed
LigandPNGBDBM50556732(CHEMBL4750435)copy SMILES
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of PTPN2 (unknown origin) pre-incubated for 20 mins followed by fluorescence substrate addition and measured after 120 mins by DiFMUP assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171QPPubMed
LigandPNGBDBM50556738(CHEMBL4743897)copy SMILES
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171QPPubMed
LigandPNGBDBM50556752(CHEMBL4760652)copy SMILES
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171QPPubMed
LigandPNGBDBM50556740(CHEMBL4776595)copy SMILES
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171QPPubMed
LigandPNGBDBM50556742(CHEMBL4788228)copy SMILES
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171QPPubMed
LigandPNGBDBM50342004(4-(2-(3-(4-nitrophenyl)-5-oxo-1-phenyl-1H-pyrazol-...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 20 uM DiFMUP by DiFMUP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171QPPubMed
TargetDual specificity protein phosphatase 22(Homo sapiens (Human))TBA
LigandPNGBDBM50556732(CHEMBL4750435)copy SMILES
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of DUSP22 (unknown origin) pre-incubated for 20 mins followed by fluorescence substrate addition and measured after 120 mins by DiFMUP ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171QPPubMed
LigandPNGBDBM50556753(CHEMBL4786030)copy SMILES
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171QPPubMed
LigandPNGBDBM50556732(CHEMBL4750435)copy SMILES
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 20 uM DiFMUP by DiFMUP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171QPPubMed
LigandPNGBDBM50341989(3-(3,5-DIBROMO-4-HYDROXY-BENZOYL)-2-ETHYL-BENZOFUR...)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171QPPubMed
LigandPNGBDBM50556747(CHEMBL4785204)copy SMILES
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171QPPubMed
LigandPNGBDBM50556751(CHEMBL4786693)copy SMILES
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171QPPubMed
LigandPNGBDBM50342003(CHEMBL501993 | NSC-87877 | disodium 8-hydroxy-7-[(...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 20 uM DiFMUP by DiFMUP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171QPPubMed
LigandPNGBDBM50556727(CHEMBL4758364)copy SMILES
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 20 uM DiFMUP by DiFMUP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171QPPubMed
LigandPNGBDBM50556726(CHEMBL4754721)copy SMILES
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 20 uM DiFMUP by DiFMUP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171QPPubMed
LigandPNGBDBM50556750(CHEMBL4750922)copy SMILES
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171QPPubMed
LigandPNGBDBM50556744(CHEMBL4762054)copy SMILES
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171QPPubMed
LigandPNGBDBM50556739(CHEMBL4750590)copy SMILES
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171QPPubMed
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