Compile Data Set for Download or QSAR
Found 347 with Last Name = 'herp' and Initial = 'd'
TargetHistone deacetylase 8(Homo sapiens (Human))TBA
LigandPNGBDBM50534338(CHEMBL4534486)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human recombinant HDAC8 using H2N-Arg-His-Lys(Ac)-Lys(Ac)-AMC as substrate after 90 mins by fluorescence based micro plate assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD7363PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50591852(CHEMBL5188540)copy SMILES
Affinity DataIC50: 3.40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC655WPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM22449(CHEMBL356769 | N-(4-{(2R,4R,6S)-4-{[(4,5-diphenyl-...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Antagonist activity at 5-HT3 receptor in guinea pig ileum muscleMore data for this Ligand-Target Pair
In DepthDetails
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM22449(CHEMBL356769 | N-(4-{(2R,4R,6S)-4-{[(4,5-diphenyl-...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human HDAC6 using RHKKAc fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50513919(CHEMBL4457162)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))TBA
LigandPNGBDBM50510962(CHEMBL4454646)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD7363PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50252396(CHEMBL4077645)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human HDAC6 using Z-(Ac)Lys-AMC as substrate after 90 mins by fluorescence based micro plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD7363PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50562487(CHEMBL4757504)copy SMILES
Affinity DataIC50: 6.90nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 cells using Z-(Ac)Lys-AMC as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50RNPPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM22449(CHEMBL356769 | N-(4-{(2R,4R,6S)-4-{[(4,5-diphenyl-...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50517576(CHEMBL4468273)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50517583(CHEMBL4556275)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50517567(CHEMBL4545246)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50517585(CHEMBL4443794)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetPolyamine deacetylase HDAC10(Danio rerio)TBA
LigandPNGBDBM50596817(CHEMBL5184156)copy SMILES
Affinity DataIC50: 11nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50517572(CHEMBL4439108)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50562491(CHEMBL4744710)copy SMILES
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 cells using Z-(Ac)Lys-AMC as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50RNPPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50517570(CHEMBL4530950)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50517574(CHEMBL4444811)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50517578(CHEMBL4546254)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50538729(CHEMBL4649617)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human HDAC6 using Z-(Ac)Lys-AMC as substrate after 90 mins by fluorescence based micro plate assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD7363PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human HDAC6 using RHKKAc fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50517569(CHEMBL4450965)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50517577(CHEMBL4442266)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50517581(CHEMBL4581606)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50517566(CHEMBL4436946)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50591853(CHEMBL5176595)copy SMILES
Affinity DataIC50: 19nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC655WPubMed
TargetPolyamine deacetylase HDAC10(Danio rerio)TBA
LigandPNGBDBM50596819(CHEMBL5173958)copy SMILES
Affinity DataIC50: 20nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8CB7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50591850(CHEMBL5184498)copy SMILES
Affinity DataIC50: 21nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC655WPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50517568(CHEMBL4438566)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetPolyamine deacetylase HDAC10(Danio rerio)TBA
LigandPNGBDBM50596815(CHEMBL5208990)copy SMILES
Affinity DataIC50: 24nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50517565(CHEMBL4472834)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50562489(CHEMBL4750401)copy SMILES
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 cells using Z-(Ac)Lys-AMC as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50RNPPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))TBA
LigandPNGBDBM50246866(CHEMBL4078458 | US11505523, Compound 22d)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of human HDAC8 (1 to 377 residues) expressed in Escherichia coli BL21(DE3) using Boc-Lys(TFA)-AMC as substrate preincubated for 5 mins fol...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0BQJPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))TBA
LigandPNGBDBM50164532(CHEMBL3797516)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0BQJPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))TBA
LigandPNGBDBM50246866(CHEMBL4078458 | US11505523, Compound 22d)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of human recombinant HDAC8 using H2N-Arg-His-Lys(Ac)-Lys(Ac)-AMC as substrate after 90 mins by fluorescence based micro plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD7363PubMed
TargetPolyamine deacetylase HDAC10(Danio rerio)TBA
LigandPNGBDBM50596818(CHEMBL5207713)copy SMILES
Affinity DataIC50: 29nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50409064(CHEMBL5269954)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Antagonist activity at Alpha-1B adrenoceptor in Wistar rat spleen assessed as phenylephrine induced contractions after 30 minsMore data for this Ligand-Target Pair
In DepthDetails
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of full length N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using ZMAL as substrate incubated for 90 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7SG5PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full length HDAC6 expressed in insect SF9 cells using fluorogenic ZMAL as substrate after 90 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5CJ3PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50517571(CHEMBL4551531)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50517573(CHEMBL4436806)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50260597(CHEMBL4079901)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant human HDAC1 using Z-(Ac)Lys-AMC as substrate after 90 mins by fluorescence based micro plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD7363PubMed
TargetPolyamine deacetylase HDAC10(Danio rerio)TBA
LigandPNGBDBM50596824(CHEMBL5188463)copy SMILES
Affinity DataIC50: 33nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8CB7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Antagonist activity at 5-HT3 receptor in guinea pig ileum muscleMore data for this Ligand-Target Pair
In DepthDetails DrugBank
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Antagonist activity at Alpha-1D adrenoceptor in Wistar rat thoracic aorta assessed as noradrenaline induced contractions after 30 minsMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50562492(CHEMBL4752147)copy SMILES
Affinity DataIC50: 33nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 cells using Z-(Ac)Lys-AMC as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50RNPPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM19410(CHEMBL27759 | MS-275 | US11377423, MS-275 | US1167...)copy SMILEScopy InChI
Affinity DataIC50: 34nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8CB7PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))TBA
LigandPNGBDBM50246847(CHEMBL4089635)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0BQJPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50517579(CHEMBL4442157)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
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