Compile Data Set for Download or QSAR
Found 16 with Last Name = 'meininger' and Initial = 'd'
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50248569((1-(((R)-3-methyl-4-(4-((S)-1,1,1-trifluoro-2-hydr...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Inhibition of human 11beta-HSD1 using variable cofactor NADPH concentration by Lineweaver burk plotMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50248569((1-(((R)-3-methyl-4-(4-((S)-1,1,1-trifluoro-2-hydr...)copy SMILEScopy InChI
Affinity DataKi:  2.70nMAssay Description:Inhibition of human 11beta-HSD1 using variable substrate cortisol concentration by Lineweaver burk plotMore data for this Ligand-Target Pair
Target4-hydroxy-tetrahydrodipicolinate reductase(Escherichia coli)
Triad Therapeutics, Inc

LigandPNGBDBM59098(Bi-ligand, 1)copy SMILEScopy InChI
Affinity DataKi:  26nMpH: 7.4Assay Description:All reactions were monitored spectrophotometrically at 340 nm by using initial rates from the first 5% of reaction.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K9360MPubMed
TargetQuinone-dependent D-lactate dehydrogenase(Escherichia coli)
Triad Therapeutics, Inc

LigandPNGBDBM59099(Bi-ligand, 2)copy SMILEScopy InChI
Affinity DataKi:  42nMpH: 7.4Assay Description:All reactions were monitored spectrophotometrically at 340 nm by using initial rates from the first 5% of reaction.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K9360MPubMed
Target4-hydroxy-tetrahydrodipicolinate reductase(Escherichia coli)
Triad Therapeutics, Inc

LigandPNGBDBM59101(Bi-ligand, 4)copy SMILEScopy InChI
Affinity DataKi:  100nMpH: 7.4Assay Description:All reactions were monitored spectrophotometrically at 340 nm by using initial rates from the first 5% of reaction.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K9360MPubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
Triad Therapeutics, Inc

LigandPNGBDBM59100(Bi-ligand, 3)copy SMILEScopy InChI
Affinity DataKi:  202nMpH: 7.4Assay Description:All reactions were monitored spectrophotometrically at 340 nm by using initial rates from the first 5% of reaction.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K9360MPubMed
TargetQuinone-dependent D-lactate dehydrogenase(Escherichia coli)
Triad Therapeutics, Inc

LigandPNGBDBM59101(Bi-ligand, 4)copy SMILEScopy InChI
Affinity DataKi:  620nMpH: 7.4Assay Description:All reactions were monitored spectrophotometrically at 340 nm by using initial rates from the first 5% of reaction.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K9360MPubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
Triad Therapeutics, Inc

LigandPNGBDBM59101(Bi-ligand, 4)copy SMILEScopy InChI
Affinity DataKi:  7.90E+3nMpH: 7.4Assay Description:All reactions were monitored spectrophotometrically at 340 nm by using initial rates from the first 5% of reaction.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K9360MPubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
Triad Therapeutics, Inc

LigandPNGBDBM59099(Bi-ligand, 2)copy SMILEScopy InChI
Affinity DataKi:  1.00E+4nMpH: 7.4Assay Description:All reactions were monitored spectrophotometrically at 340 nm by using initial rates from the first 5% of reaction.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K9360MPubMed
TargetQuinone-dependent D-lactate dehydrogenase(Escherichia coli)
Triad Therapeutics, Inc

LigandPNGBDBM59100(Bi-ligand, 3)copy SMILEScopy InChI
Affinity DataKi:  1.20E+4nMpH: 7.4Assay Description:All reactions were monitored spectrophotometrically at 340 nm by using initial rates from the first 5% of reaction.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K9360MPubMed
Target4-hydroxy-tetrahydrodipicolinate reductase(Escherichia coli)
Triad Therapeutics, Inc

LigandPNGBDBM59100(Bi-ligand, 3)copy SMILEScopy InChI
Affinity DataKi: >2.50E+4nMpH: 7.4Assay Description:All reactions were monitored spectrophotometrically at 340 nm by using initial rates from the first 5% of reaction.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K9360MPubMed
Target4-hydroxy-tetrahydrodipicolinate reductase(Escherichia coli)
Triad Therapeutics, Inc

LigandPNGBDBM59099(Bi-ligand, 2)copy SMILEScopy InChI
Affinity DataKi: >5.00E+4nMpH: 7.4Assay Description:All reactions were monitored spectrophotometrically at 340 nm by using initial rates from the first 5% of reaction.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K9360MPubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
Triad Therapeutics, Inc

LigandPNGBDBM59098(Bi-ligand, 1)copy SMILEScopy InChI
Affinity DataKi: >5.00E+4nMpH: 7.4Assay Description:All reactions were monitored spectrophotometrically at 340 nm by using initial rates from the first 5% of reaction.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K9360MPubMed
TargetQuinone-dependent D-lactate dehydrogenase(Escherichia coli)
Triad Therapeutics, Inc

LigandPNGBDBM59098(Bi-ligand, 1)copy SMILEScopy InChI
Affinity DataKi:  5.50E+4nMpH: 7.4Assay Description:All reactions were monitored spectrophotometrically at 340 nm by using initial rates from the first 5% of reaction.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K9360MPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50248569((1-(((R)-3-methyl-4-(4-((S)-1,1,1-trifluoro-2-hydr...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of FLAG tagged human recombinant 11beta-HSD1 reductase activity expressed in Trichoplusia ni Hi5 cellsMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50263346((3-(1-(4-fluorophenyl)cyclopropyl)-4-isopropyl-5-(...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of FLAG tagged human recombinant 11beta-HSD1 reductase activity expressed in Trichoplusia ni Hi5 cellsMore data for this Ligand-Target Pair