Compile Data Set for Download or QSAR
Found 224 with Last Name = 'schade' and Initial = 'd'
TargetCasein kinase I isoform delta(Homo sapiens (Human))TBA
LigandPNGBDBM50105742(4-[4-(4-Fluoro-phenyl)-5-(2-methoxy-pyrimidin-4-yl...)copy SMILEScopy InChI
Affinity DataKi:  25nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84GZFPubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))TBA
LigandPNGBDBM50284506(4-[5-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl...)copy SMILEScopy InChI
Affinity DataKi:  39nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84GZFPubMed
TargetCasein kinase I isoform alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50105742(4-[4-(4-Fluoro-phenyl)-5-(2-methoxy-pyrimidin-4-yl...)copy SMILEScopy InChI
Affinity DataKi:  501nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84GZFPubMed
TargetCasein kinase I isoform alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50284506(4-[5-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl...)copy SMILEScopy InChI
Affinity DataKi:  650nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84GZFPubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50519933(CHEMBL4444007)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD5158PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50519934(CHEMBL4461206)copy SMILEScopy InChI
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD5158PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50240715((S)-2-Amino-5-but-3-enimidoylamino-pentanoic acid ...)copy SMILEScopy InChI
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PG3PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM235685(hDDAH inhibitor, 1a)copy SMILEScopy InChI
Affinity DataKi:  2.00E+3nM ΔG°:  -33.8kJ/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B3064PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50240715((S)-2-Amino-5-but-3-enimidoylamino-pentanoic acid ...)copy SMILEScopy InChI
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD5158PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50519932(CHEMBL4449638)copy SMILEScopy InChI
Affinity DataKi:  9.00E+3nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD5158PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM141899(US8921421, L-257 | hDDAH inhibitor, 2a)copy SMILEScopy InChI
Affinity DataKi:  1.30E+4nM IC50: 2.90E+4nMpH: 7.4Assay Description:This assay was used to determine the inhibiting effect of the inhibitors in a concentration of 1 mM. A standard incubation mixture consisted of 75 &#...More data for this Ligand-Target Pair
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM141899(US8921421, L-257 | hDDAH inhibitor, 2a)copy SMILEScopy InChI
Affinity DataKi:  1.30E+4nM ΔG°:  -29.0kJ/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50240959((S)-2-Amino-5-[N'-(2-methoxy-ethyl)-guanidino]-pen...)copy SMILEScopy InChI
Affinity DataKi:  1.30E+4nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD5158PubMedMMDB
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50240959((S)-2-Amino-5-[N'-(2-methoxy-ethyl)-guanidino]-pen...)copy SMILEScopy InChI
Affinity DataKi:  1.30E+4nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PG3PubMedMMDB
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM235691(hDDAH inhibitor, 2e)copy SMILEScopy InChI
Affinity DataKi:  1.70E+4nM ΔG°:  -28.3kJ/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B3064PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50254452(CHEMBL197234 | N-omega-propargyl-L-arginine)copy SMILEScopy InChI
Affinity DataKi:  1.70E+4nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PG3PubMed
TargetArginase-1(Bos taurus)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50375814(CHEMBL260628)copy SMILEScopy InChI
Affinity DataKi:  1.71E+4nMAssay Description:Inhibition of bovine liver arginaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5GXNPubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM141900(US8921421, 3)copy SMILEScopy InChI
Affinity DataKi:  1.80E+4nM IC50: 7.00E+4nMpH: 7.4Assay Description:This assay was used to determine the inhibiting effect of the inhibitors in a concentration of 1 mM. A standard incubation mixture consisted of 75 &#...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GH9GP9US Patent
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM141900(US8921421, 3)copy SMILEScopy InChI
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD5158PubMed
TargetArginase-1(Bos taurus)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50230418(CHEMBL260629 | N(gamma)-hydroxy-L-arginine | N-OME...)copy SMILEScopy InChI
Affinity DataKi:  3.00E+4nMAssay Description:Inhibition of bovine liver arginaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5GXNPubMedMMDB
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50255074((S)-2-Amino-5-butyrimidoylamino-pentanoic acid | C...)copy SMILEScopy InChI
Affinity DataKi:  3.20E+4nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PG3PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM152700((S)-2-Amino-5-butyrimidamidopentanoic acid (9) | h...)copy SMILEScopy InChI
Affinity DataKi:  3.20E+4nM ΔG°:  -26.7kJ/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B3064PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM235686(hDDAH inhibitor, 1c)copy SMILEScopy InChI
Affinity DataKi:  3.60E+4nM ΔG°:  -26.4kJ/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B3064PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50254449(CHEMBL456882 | N5-(1-iminopent-3-enyl)-L-ornithine)copy SMILEScopy InChI
Affinity DataKi:  3.60E+4nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PG3PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50254451(CHEMBL106423 | N-omega-(but-3-enyl)-L-arginine)copy SMILEScopy InChI
Affinity DataKi:  5.70E+4nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PG3PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM235690(hDDAH inhibitor, 2d)copy SMILEScopy InChI
Affinity DataKi:  5.70E+4nM ΔG°:  -25.2kJ/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B3064PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50254451(CHEMBL106423 | N-omega-(but-3-enyl)-L-arginine)copy SMILEScopy InChI
Affinity DataKi:  5.70E+4nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD5158PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50240714((2S)-5-{[(allylamino)(iminio)methyl]amino}-2-ammon...)copy SMILEScopy InChI
Affinity DataKi:  5.80E+4nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PG3PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM235689(hDDAH inhibitor, 2c)copy SMILEScopy InChI
Affinity DataKi:  5.80E+4nM ΔG°:  -25.2kJ/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B3064PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50519930(CHEMBL4544147)copy SMILEScopy InChI
Affinity DataKi:  5.90E+4nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD5158PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50519936(CHEMBL4442120)copy SMILEScopy InChI
Affinity DataKi:  7.30E+4nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD5158PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50240716((S)-2-Amino-5-(N'-propyl-guanidino)-pentanoic acid...)copy SMILEScopy InChI
Affinity DataKi:  9.00E+4nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PG3PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM235688(hDDAH inhibitor, 2b)copy SMILEScopy InChI
Affinity DataKi:  9.00E+4nM ΔG°:  -24.0kJ/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B3064PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50254450((S)-2-Amino-5-propionimidoylamino-pentanoic acid |...)copy SMILEScopy InChI
Affinity DataKi:  1.45E+5nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM152699((S)-2-Amino-5-propionimidamidopentanoic acid (8) |...)copy SMILEScopy InChI
Affinity DataKi:  1.45E+5nM ΔG°:  -22.8kJ/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50519935(CHEMBL4537472)copy SMILEScopy InChI
Affinity DataKi:  1.56E+5nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD5158PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50519929(CHEMBL4517869)copy SMILEScopy InChI
Affinity DataKi:  4.89E+5nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD5158PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM60960(hDDAH inhibitor, 2f)copy SMILEScopy InChI
Affinity DataKi:  6.06E+5nM ΔG°:  -19.1kJ/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B3064PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM235693(hDDAH inhibitor, 2h)copy SMILEScopy InChI
Affinity DataKi:  7.64E+5nM ΔG°:  -18.5kJ/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B3064PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50519928(CHEMBL4558445)copy SMILEScopy InChI
Affinity DataKi:  7.68E+5nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD5158PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50519931(CHEMBL4554366)copy SMILEScopy InChI
Affinity DataKi:  9.83E+5nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD5158PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM152697((S)-5-Acetimidamido-2-aminopentanoic acid (4, L-NI...)copy SMILEScopy InChI
Affinity DataKi:  1.16E+6nM ΔG°:  -17.4kJ/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B3064PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50519939(CHEMBL4557528)copy SMILEScopy InChI
Affinity DataKi:  1.45E+6nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD5158PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM235692(hDDAH inhibitor, 2g)copy SMILEScopy InChI
Affinity DataKi:  1.97E+6nM ΔG°:  -16.1kJ/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B3064PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50519938(CHEMBL4443195)copy SMILEScopy InChI
Affinity DataKi:  2.76E+6nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD5158PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50519937(CHEMBL4582190)copy SMILEScopy InChI
Affinity DataKi:  2.82E+6nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD5158PubMed
TargetNeuraminidase(Influenza A virus)
Christian-Albrechts University of Kiel

Curated by ChEMBL
LigandPNGBDBM50330326((4S,5R,6R)-5-Acetylamino-4-guanidino-6-((1R,3R)-1,...)copy SMILEScopy InChI
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of neuraminidase in Influenza A virus A/Jena/5258/2009(H1N1) using Na-star as substrate preincubated for 10 to 30 mins followed by substra...More data for this Ligand-Target Pair
TargetNeuraminidase(Influenza A virus)
Christian-Albrechts University of Kiel

Curated by ChEMBL
LigandPNGBDBM50330326((4S,5R,6R)-5-Acetylamino-4-guanidino-6-((1R,3R)-1,...)copy SMILEScopy InChI
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of neuraminidase in Influenza A virus A/Jena/5555/09(H1N1) using Na-star as substrate preincubated for 10 to 30 mins followed by substrate...More data for this Ligand-Target Pair
TargetNeuraminidase(Influenza A virus)
Christian-Albrechts University of Kiel

Curated by ChEMBL
LigandPNGBDBM50330326((4S,5R,6R)-5-Acetylamino-4-guanidino-6-((1R,3R)-1,...)copy SMILEScopy InChI
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of neuraminidase in Influenza A virus A/HH/1580/09(H1N1) using Na-star as substrate preincubated for 10 to 30 mins followed by substrate a...More data for this Ligand-Target Pair
TargetNeuraminidase(Influenza A virus)
Christian-Albrechts University of Kiel

Curated by ChEMBL
LigandPNGBDBM4994((3R,4R,5S)-5-amino-4-acetamido-3-(pentan-3-yloxy)c...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Inhibition of neuraminidase in Influenza A virus A/Jena/5555/09(H1N1) using Na-star as substrate preincubated for 10 to 30 mins followed by substrate...More data for this Ligand-Target Pair
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