TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Universit£ di Bologna
Curated by ChEMBL
Universit£ di Bologna
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of RSK2 using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate ...More data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Universit£ di Bologna
Curated by ChEMBL
Universit£ di Bologna
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of RSK1 using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Universit£ di Bologna
Curated by ChEMBL
Universit£ di Bologna
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of CHK1 using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Aurora A using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence micropl...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Universit£ di Bologna
Curated by ChEMBL
Universit£ di Bologna
Curated by ChEMBL
Affinity DataIC50: 0.830nMAssay Description:Inhibition of c-Src using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of LCK using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate a...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Universit£ di Bologna
Curated by ChEMBL
Universit£ di Bologna
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of c-Src using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of LCK using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate a...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Inhibition of ALK using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Universit£ di Bologna
Curated by ChEMBL
Universit£ di Bologna
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Inhibition of CHK2 using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate ...More data for this Ligand-Target Pair
Affinity DataIC50: 8.60nMAssay Description:Inhibition of ZAP70 using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate...More data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:Inhibition of LCK using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Universit£ di Bologna
Curated by ChEMBL
Universit£ di Bologna
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of CHK2 using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate ...More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Inhibition of ALK using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Universit£ di Bologna
Curated by ChEMBL
Universit£ di Bologna
Curated by ChEMBL
Affinity DataIC50: 77nMAssay Description:Inhibition of CHK1 using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate ...More data for this Ligand-Target Pair
Affinity DataIC50: 80nMpH: 7.5 T: 2°CAssay Description:NSC 109555 was diluted in water. All other drugs were dissolved in DMSO, in which case the final DMSO concentration in reactions was 10%, and the con...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMpH: 7.5 T: 2°CAssay Description:NSC 109555 was diluted in water. All other drugs were dissolved in DMSO, in which case the final DMSO concentration in reactions was 10%, and the con...More data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Universit£ di Bologna
Curated by ChEMBL
Universit£ di Bologna
Curated by ChEMBL
Affinity DataIC50: 131nMAssay Description:Inhibition of RSK1 using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate ...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Universit£ di Bologna
Curated by ChEMBL
Universit£ di Bologna
Curated by ChEMBL
Affinity DataIC50: 153nMAssay Description:Inhibition of c-Src using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate...More data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Universit£ di Bologna
Curated by ChEMBL
Universit£ di Bologna
Curated by ChEMBL
Affinity DataIC50: 184nMAssay Description:Inhibition of RSK2 using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate ...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMpH: 7.2 T: 2°CAssay Description:The IMAP Screening Express Kit (Molecular Devices, Sunnyvale, CA) was used for the high-throughput screening experiments. Compounds from the Developm...More data for this Ligand-Target Pair
Affinity DataIC50: 240nMpH: 7.5 T: 2°CAssay Description:NSC 109555 was diluted in water. All other drugs were dissolved in DMSO, in which case the final DMSO concentration in reactions was 10%, and the con...More data for this Ligand-Target Pair
Affinity DataIC50: 405nMAssay Description:Inhibition of c-Met using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate...More data for this Ligand-Target Pair
Affinity DataIC50: 420nMpH: 7.5 T: 2°CAssay Description:NSC 109555 was diluted in water. All other drugs were dissolved in DMSO, in which case the final DMSO concentration in reactions was 10%, and the con...More data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Universit£ di Bologna
Curated by ChEMBL
Universit£ di Bologna
Curated by ChEMBL
Affinity DataIC50: 607nMAssay Description:Inhibition of RSK2 using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate ...More data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Universit£ di Bologna
Curated by ChEMBL
Universit£ di Bologna
Curated by ChEMBL
Affinity DataIC50: 970nMAssay Description:Inhibition of RSK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assayMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Universit£ di Bologna
Curated by ChEMBL
Universit£ di Bologna
Curated by ChEMBL
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of RSK1 using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate ...More data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Universit£ di Bologna
Curated by ChEMBL
Universit£ di Bologna
Curated by ChEMBL
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of RSK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.84E+3nMAssay Description:Inhibition of Aurora A using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence micropl...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Universit£ di Bologna
Curated by ChEMBL
Universit£ di Bologna
Curated by ChEMBL
Affinity DataIC50: 1.96E+3nMAssay Description:Inhibition of CHK2 using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate ...More data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Universit£ di Bologna
Curated by ChEMBL
Universit£ di Bologna
Curated by ChEMBL
Affinity DataIC50: 2.15E+3nMAssay Description:Inhibition of RSK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.63E+3nMAssay Description:Inhibition of Aurora A using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence micropl...More data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Universit£ di Bologna
Curated by ChEMBL
Universit£ di Bologna
Curated by ChEMBL
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of RSK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assayMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Universit£ di Bologna
Curated by ChEMBL
Universit£ di Bologna
Curated by ChEMBL
Affinity DataIC50: 2.89E+3nMAssay Description:Inhibition of RSK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assayMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Universit£ di Bologna
Curated by ChEMBL
Universit£ di Bologna
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of RSK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assayMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Universit£ di Bologna
Curated by ChEMBL
Universit£ di Bologna
Curated by ChEMBL
Affinity DataIC50: 3.13E+3nMAssay Description:Inhibition of RSK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assayMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Universit£ di Bologna
Curated by ChEMBL
Universit£ di Bologna
Curated by ChEMBL
Affinity DataIC50: 3.58E+3nMAssay Description:Inhibition of RSK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assayMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Universit£ di Bologna
Curated by ChEMBL
Universit£ di Bologna
Curated by ChEMBL
Affinity DataIC50: 3.76E+3nMAssay Description:Inhibition of RSK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assayMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Universit£ di Bologna
Curated by ChEMBL
Universit£ di Bologna
Curated by ChEMBL
Affinity DataIC50: 3.93E+3nMAssay Description:Inhibition of RSK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assayMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Universit£ di Bologna
Curated by ChEMBL
Universit£ di Bologna
Curated by ChEMBL
Affinity DataIC50: 4.53E+3nMAssay Description:Inhibition of RSK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assayMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Universit£ di Bologna
Curated by ChEMBL
Universit£ di Bologna
Curated by ChEMBL
Affinity DataIC50: 5.66E+3nMAssay Description:Inhibition of RSK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assayMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Universit£ di Bologna
Curated by ChEMBL
Universit£ di Bologna
Curated by ChEMBL
Affinity DataIC50: 5.85E+3nMAssay Description:Inhibition of RSK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assayMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Universit£ di Bologna
Curated by ChEMBL
Universit£ di Bologna
Curated by ChEMBL
Affinity DataIC50: 5.93E+3nMAssay Description:Inhibition of RSK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assayMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Universit£ di Bologna
Curated by ChEMBL
Universit£ di Bologna
Curated by ChEMBL
Affinity DataIC50: 5.97E+3nMAssay Description:Inhibition of RSK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assayMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Universit£ di Bologna
Curated by ChEMBL
Universit£ di Bologna
Curated by ChEMBL
Affinity DataIC50: 6.03E+3nMAssay Description:Inhibition of RSK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assayMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Universit£ di Bologna
Curated by ChEMBL
Universit£ di Bologna
Curated by ChEMBL
Affinity DataIC50: 6.43E+3nMAssay Description:Inhibition of RSK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Universit£ di Bologna
Curated by ChEMBL
Universit£ di Bologna
Curated by ChEMBL
Affinity DataIC50: 6.58E+3nMAssay Description:Inhibition of CHK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assayMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Universit£ di Bologna
Curated by ChEMBL
Universit£ di Bologna
Curated by ChEMBL
Affinity DataIC50: 7.32E+3nMAssay Description:Inhibition of RSK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assayMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Universit£ di Bologna
Curated by ChEMBL
Universit£ di Bologna
Curated by ChEMBL
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of RSK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assayMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Universit£ di Bologna
Curated by ChEMBL
Universit£ di Bologna
Curated by ChEMBL
Affinity DataIC50: 8.26E+3nMAssay Description:Inhibition of RSK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assayMore data for this Ligand-Target Pair